艾可清胶囊提取工艺

目的:优选中药复方制剂艾可清胶囊的提取工艺.方法:以淫羊藿苷、虎杖苷、甘草酸、黄芩苷的提取率为指标,采用正交试验设计筛选提取工艺条件,结合综合评分优选最佳工艺条件.结果:优选出的提取条件为30倍量65％乙醇加热回流提取淫羊藿2次,每次3h,提取液减压浓缩至相对密度为1.10(60℃)；3倍量20％乙醇室温放置8h去除叶绿素；10倍量80％乙醇提取虎杖、黄芩、甘草等混合药材粗粉3次,每次2h.结论:经中试验证,指标成分提取率为66％ ～ 88％,表明优选工艺可行.

Extracting Technology for Aikeqing Capsule

Objective:To optimize extraction technology of Aikeqing capsule,a compound preparation of Chinese medicine.Method:Orthogonal test was used to evaluate extraction technology with yield of icariin,polydatin,glycyrrhizic acid and baicalin as indexes,optimum technology conditions were optimized by combined with comprehensive scoring method.Result:Optimum extraction conditions were as follows:H.Epimedii was heating refluxing extracted 2 times with 30 times the amount of 65% ethanol for 3 hours each time,extraction solution was concentrated in vacuum to relative density of 1.10(60 ℃);then treated with 3 times the amount of 20% ethanol staying for 8 hours to filter off chlorophyll;extracted 3 times of mixed herbs powder of R.polygoni cuspidate,R.scutellaria,and R.glycyrrhizae with 10 times the amount of 80% ethanol for two hours each time.Conclusion:After tested by pilot,yield of maker compounds were 66%～88%,it showed optimized technology was feasible.