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| 丙型肝炎病毒血清学分型应用的可行性研究 | |
| 引用本文： | 张天泰,张庶民,高评,谢晨,陈青锋,庄辉. 丙型肝炎病毒血清学分型应用的可行性研究[J]. 中华实验和临床病毒学杂志, 2001, 15(4): 355-356 |
| 作者姓名： | 张天泰 张庶民 高评 谢晨 陈青锋 庄辉 |
| 作者单位： | 1. 兰州医学院附属一院, 2. 中国药品生物制品检定所 3. 北京医科大学微生物系 |
| 摘 要： | 目的 探讨丙型肝炎病毒血清学分型的可行性。方法 应用EIA法对兰州地区148例抗－HCV阳性者进行血清学分型。结果 血清学方法的分型率为56．08％（83／148），其中血清1型占50．60％（42／83），血清2型占43．47％（36／83），1＋2混合型占6．03％（5／83）。对其中70例HCVRNA阳性血清的基因型与血清型结果进行比较，二者完全相符。结论 丙型肝炎病毒的血清学分型具有一定的临床应用价值。 |
| 关 键 词： | 丙型肝炎 丙型肝炎病毒 血清分型 可行性研究 |
| 修稿时间： | 2000-04-19 |
Study on applicability of hepatitis C virus serotyping |
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| T Zhang,S Zhang,P Gao. Study on applicability of hepatitis C virus serotyping[J]. Chinese journal of experimental and clinical virology, 2001, 15(4): 355-356 | |
| Authors: | T Zhang S Zhang P Gao |
| Affiliation: | Department of Infectious Disease, First Hospital of Lanzhou Medical College, Lanzhou 730000,China. |
| Abstract: | Objective To explore the applicability of HCV serotyping.Methods Enzyme immunoassay (EIA) was used to detect the serotypes of 148 patients with viral hepatitis C.Results 56^08%(83/148) patients were sero typed,of whom 50^06%(42/83) were identified to be serotype 1,43^37%(36/83) serotype 2,and 6^03%(5/83)mixed serotype 1 and 2.The sera from 70 HCV RNA|postitive patients out of the 83 ones who were successfully serotyped were detected for genotyping.The results were completely consistent between serotyping and genotyping.Conclusion Serotyping of HCV has its clinical applicable value. |
| Keywords: | Hepatitis C Hepatitis C virus Serotyping |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |