洗发类化妆品的刺激性研究

目的：通过判定洗发类化妆品对皮肤、粘膜的刺激性，来确保消费者使用安全可靠的产品。方法：根据中华人民共和国国家标准《化妆品安全性评价程度和方法》中，急性皮肤刺激试验方法、眼刺激试验方法和多次皮肤刺激试验方法。结果：三种类型的洗发香波对试验兔的皮肤一次刺激反应积分均值为零，属无刺激性。其中单纯型洗发香波的急性眼刺激试验属无刺激性，而止痒型和三效合一型洗发香波的急性眼刺激试验属轻刺激性。通过多次皮肤刺激试验，可见三种类型洗发香波均出现皮肤增厚、变硬等症状。结论：使用洗发类化妆品，应防止误入眼内，用后应彻底清洗干净。

Study on Irritability of Shampoo Cosmetics

Objective To study the irritability of shampoo cosmetics to skin and mucous membrane. Method The irritabilities of 3 kinds of shampoo cosmetics were examined by acute skin irritation test, eye irritation test and mutiple_time skin irritation test according to the Procedures and Methods of Safty Evaluation for Cosmetics of National Standard. Results Tested 3 kinds of shampoo cosmetics showed no irritability to rabbits in one_time skin irritation test with skin_irritation scores of zero. In acute eye irritation test, the shampoo cosmetics with simple function of cleaning hair showed no irritability, but the shampoo cosmetics with multiple functions such as antipruritus and triad effectiveness showed slight irritabibity. Thickened and hardened skin were observed in the tested locations of rabbits'skin treated by any one of tested 3 kinds of shampoo cosmetics in multiple_time skin irritation test.Conclusion The shampoo cosmetics must be kept away from eyes, and must be cleaned away from the surface of skin completely after use.