重症急性胰腺炎应用短期腹腔灌洗治疗效果观察．

目的：观察和分析短期腹腔灌洗治疗重症急性胰腺炎患者的临床效果。方法：选取2012年12月-2014年4月收治的96例重症急性胰腺炎患者，按照患者住院时间先后顺序分为对照组和治疗组。对照组：采用常规治疗，但未实施灌洗。治疗组：在常规治疗基础上实施短期腹腔灌洗治疗。观察两组患者治疗前后APACHEII变化及血清CRP水平变化、临床指标改善、并发症等情况。结果：治疗前，治疗组APACHEII积分和CRP分别为（14．38±6．47）分、（269．79±52．01）mg／L，与对照组的（14．42±6．51）分、（269．87±51．96）mg／L比较差异无统计学意义（P〉0．05）；治疗后，治疗组APACHEII积分和CRP分别为（6．64±2．17）分、（64．27±10．61）mg／L，与对照组的（9．65±2．47）分、（127．61±32．21）mg／L比较差异有统计学意义（P〈0．05）。治疗组患者临床指标改善和并发症发生率与对照组比较差异有统计学意义（P〈0．05）。结论：采用短期腹腔灌洗治疗重症急性胰腺炎，可有效改善患者临床各项指标，降低患者APACHEII积分和CRP水平，减少并发症发生，促进患者康复。

Effect Observation of Short-term Abdominal Cavity Lavage in the Treatment of Severe Acute Pancreatitis

Objective： To observe the clinical effect of short-term peritoneal lavage in the treatment of severe acute pancreatitis.Method： 96 patients with severe acute panereatitis were selected in December 2012 to April 2014, they were divided into control group and treatment group according to the hospital time sequence.The control group were treated with the conventional treatment.The treatment group were treated with conventional treatment and short-term peritoneal lavage treatment.APACHEII and serum CRP level changes, clinical indicators improved, complications of two groups were observed before and after treatment.Result： Before the treatment, APACHEII scores and CRP of the treatment group were （ 14.38 ± 6.47 ） and （ 269.79 ±52.01 ） mg/L, respectively, the control group were （ 14.42 ± 6.51 ） and （ 269.87 ±51.96 ） rag/L, there were no significant differences （ P〉0.05 ） .After treatment, APACHEII scores and CRP of the treatment group were （ 6.64 ± 2.17 ） and （ 64.27 ±10.61 ） mg/L, respectively, the control group were （ 9.65 ± 2.47 ） and （ 127.61± 32.21 ） mg/L, there were significant differences （ P〈0.05 ） .There were significant differences in clinical indicators improvement and complication rates between two groups （P〈0.05） .Conclusion： Short-term peritoneal lavage treatment in the treatment of severe acute pancreatitis, can effectively improve patient clinical indicators, decrease APACHEII scores and CRP levels, reduce complications, promote patients recover.