静脉输液组间冲管液量数学模型及体外实验研究

目的:探讨静脉输液组间冲管液量的数学模型及主要影响因素。方法:推演冲管液量的数学模型并以体外实验进行验证,分别将1mL、3mL、5mL的B液注入输液管墨菲氏小壶内,然后以A液滴注冲洗,用分光光度计测定滴出液体的吸光度,当吸光度值趋于0时收集滴出的液体量,即为实际冲管液量,并与数学模型计算所得值进行比较。结果:墨菲氏小壶内B液量分别为3mL、5mL时,实际冲管液量与计算结果比较其差异均无统计学意义(P0.05)。结论:静脉输液组间冲管液量数学模型经体外实验验证,能够指导临床工作;冲管液量主要与墨菲氏小壶内的原药液体积有关,其体积越小,所需冲管液量越少。

Study of mathematic model about rinse fluid volume between intravenous transfusions and experiment in vitro

Objective： To found the mathematic model about rinse fluid volume between intravenous transfusions and the main influencing factor. Methods： We derived the mathematic model and carried out experiment in vitro. After successively infusing 1 mL, 3 mL, 5 mL B fluid into the Mofei＇s dropper and rinsing by A fluid, we used spectrophotometer to determine absorbance of fluids dropping out, collected all the drop fluid together when the absorbance approach to zero and compared with the results getting from mathematic model. Results： The comparison between practical rinse fluid volume and computation had not statistically significant （P〉0. 05） when B fluid in Mofei＇s dropper were 3 mL and 5 mL. Conclusion： The mathematic model about rinse fluid volume between intravenous transfusions can instruct the clinical works validated by experiment in vitro. Rinse fluid volume is mainly influenced by the volume of the drug＇s initial in Mofei＇s dropper. The volume of the drugs initial is smaller; the rinse fluid volume is smaller.