肺炎链球菌所致下呼吸道感染的耐药性分析

目的:调查近期天津市肺炎链球菌下呼吸道感染的耐药情况.方法:对天津市10所医院2000-2002年收治的61例肺炎链球菌所致下呼吸道感染成人患者的细菌培养结果进行回顾性分析,药敏试验采用琼脂纸片扩散法.结果:药敏结果显示,61株肺炎链球菌对青霉素的耐药率为13.1%,头孢噻肟没有耐药菌,其他β-内酰胺类抗生素的耐药率为2.9%～10.0%,红霉素的耐药率为47.1%,左氧氟沙星耐药率为17.8%, 万古霉素没有发现耐药菌.结论:青霉素仍可作为肺炎链球菌所致下呼吸道感染最有效的抗生素,喹诺酮类抗生素耐药率升高应引起高度重视.

Analysis of the drug resistance of Streptococcus pneumoniae induced lower respiratory infection

Objective: To investigate drug resistant of lower respiratory infection caused by (Streptococcus) pneumoniae in Tianjin. Methods: The antibiotic susceptibility studies of 61 cases from (respiration) (department) of 10 hospitals in Tianjin and during 2000-2002 were reviewed. KirbyBauer agar (diffusion) (method) was used. Results: The antibiotic susceptibility studies showed that the resistance rates of (Streptococcus) pneumoniae to penicillin were 13.1%. All of the strains were suscepococcus to cefotaxime. The resistance rates of Streptococcus paeumoniae to the other betalactams were 2.9.0%, to erythromycin were (higher) (47.1%), to levofloxacin were 17.8%. All of the strains were suscepococcus to vancomycin. (Conclusion): The rate of resistance to penicillin has remained low and it's an effective drug on treating (respiratory) (infection) caused by Streptococcus pneumoniae. It should pay much attention to that (fluoroquinolones) has (been) (increased) with the extensive use of antimicrobial agents.