尿微量白蛋白与冠心病支架植入术后1年再狭窄的相关性

目的:分析尿微量白蛋白（MAU）与冠心病患者行支架植入术后1年支架内再狭窄的相关性。方法: 收集2009年3月~2011年6月我科139例冠心病经皮冠状动脉介入治疗患者，支架植入术前检测患者MAU，术后1年根据患者冠状动脉造影结果分为再狭窄组和未狭窄组。结果: 再狭窄组患者MAU水平［(59±16) mg/L］显著高于未狭窄组患者［(39±15) mg/L］ （P<0.05）；再狭窄组中单支病变［(40±3) mg/L］、两支病变［(55±5) mg/L］和三支病变［(82±11) mg/L］患者MAU水平比较差异有统计学意义（P<0.05）。结论: 冠心病患者支架植入术后1年支架内再狭窄与患者支架术前的MAU水平相关，MAU是支架术后再狭窄的很好预测指标。

Correlation of microalbuminuria and coronary stenting restenosis 1 year after percutaneous coronary intervention

AIM:To explore the correlation of microalbuminuria (MAU) and stent restenosis 1 year after percutaneous coronary intervention (PCI). METHODS: Serum microalbuminuria was tested in patients prior to PCI. One year after PCI, patients were divided into restenosis group and no-restenosis group by coronary artery angiography and the results were compared. RESULTS: Serum microalbuminuria levels (59±16) mg/L in restenosis group were significantly higher than in the no-restenosis group (39±15) mg/L (t=4.316, P<0.05). Serum MAU levels were, respectively, (40±3) mg/L in single-vessel lesions, (55±5) mg/L in two-vessel lesions, and (82±11) mg/L in three-vessel lesions (F value = 61.426, P<0.05). The difference was statistically significant. CONCLUSIONS: Microalbuminuria is a good predictive index for coronary artery stent restenosis 1 year after PCI.