| 血清CA125及NSE测定对肺癌的诊断价值 |
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| 引用本文： | 王丽萍,牛秋梅,高国谦,梅其达,王瑞林.血清CA125及NSE测定对肺癌的诊断价值[J].河南大学学报(医学版),2002,21(2):20-21. |
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| 作者姓名： | 王丽萍 牛秋梅 高国谦 梅其达 王瑞林 |
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| 作者单位： | 郑州大学,第一附属医院肿瘤科,河南,郑州,450052 |
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| 基金项目： | 河南省郑州市自然科学基金项目 (2 0 0 0 15 ) |
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| 摘 要： | 目的 :观察血清CA12 5、NSE测定对肺癌的诊断价值。方法 :采用放射免疫分析法对 5 1例肺癌患者和 32例肺良性疾病患者和 6 8例健康人进行血清CA12 5、NSE水平测定。结果 :发现肺癌患者血清CA12 5、NSE水平明显高于肺良性疾病组和正常对照组 (P <0 .0 0 1) ;其增高的程度与肺癌TNM分期具有一定的相关性。血清CA12 5及NSE测定诊断肺癌的敏感性为 6 2 .72 %及 4 9.0 2 % ;特异性为 99%及 98%。结论 :联合检测血清CA12 5及NSE对肺癌的诊断、分期及疗效判断具有重要的临床价值。
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| 关 键 词： | 肺肿瘤 癌蛋白125 神经元特异性烯醇化酶 |
| 文章编号： | 1008-2867(2002)02-0020-02 |
| 修稿时间： | 2002年1月25日 |
The value of serum CA125 and NSE assays in the diagnosis of lung cancer |
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| WANG Li_Ping,NIU Qiu_Mei,GAO Guo_Qian,et al.The value of serum CA125 and NSE assays in the diagnosis of lung cancer[J].Journal of Henan University,2002,21(2):20-21. |
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| Authors: | WANG Li_Ping NIU Qiu_Mei GAO Guo_Qian |
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| Abstract: | Objectiv: To observe value of serum CA125 and NSE assays in the diagnosis of lung cancer. Methods: Contents of serum CA125? NSE were detected by immunoradiometric assay in lung cancer group (51 cases),benign pulmonary diseases(32 cases )and normal control group(68cases). Results: The serum CA125 ? NSE in lung cancer group were significantly higher than those in benign pulmonary diseases group and normal control group ( P <0.001). The degree of increase was directly associated with the lung cancer TNM stage. The sensitivity of serum CA125 and NSE assay in the diagnoses of lung cancer were 62.75% and 49.02% ;the specificity was 99% and 98%. Conclusion:Detection of serum CA125 and NSE is of clinical value for the diagnosis, staging and prognosis in lung cancer. |
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| Keywords: | Lung neoplasms CA125 NSE |
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