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艾司西酞普兰合用低剂量舒必利治疗抑郁症临床观察
引用本文:狄慧.艾司西酞普兰合用低剂量舒必利治疗抑郁症临床观察[J].中国民康医学,2012,24(6):654+689.
作者姓名:狄慧
作者单位:锦州市康宁医院,辽宁,锦州,121000
摘    要:目的:探讨艾司西酞普兰联合低剂量舒必利治疗抑郁症的疗效与不良反应。方法:将52例抑郁症患者随机分为合用组(艾司西酞普兰联合小剂量舒必利)和单用组(单用艾司西酞普兰)各26例,疗程6周。采用汉密尔顿抑郁量表(HAMD)及治疗中出现的症状量表(TESS)评定疗效与不良反应。结果:两组HAMD评分治疗后均显著下降(P<0.01),以合用组更明显;两组不良反应差异无统计学意义(P>0.05)。结论:艾司西酞普兰联合低剂量舒必利治疗抑郁症疗效好,起效快,且不良反应轻微。

关 键 词:抑郁症  艾司西酞普兰  舒必利

Clinical observation of Escitalopram combined with low dose of Sulpiride in the treatment of depression
DI Hui.Clinical observation of Escitalopram combined with low dose of Sulpiride in the treatment of depression[J].medical journal of chinese peoples health,2012,24(6):654+689.
Authors:DI Hui
Institution:DI Hui(Kangning Hospital of Jinzhou city,Jinzhou 121000,China)
Abstract:Objective:To investigate the efficacy and side effects of Escitalopram combined with low dose of Sulpiride in the treatment of depression.Methods:52 patients with depression were randomly divided into combination group(Escitalopram combined with low dose of Sulpiride,26 cases) and single group(single Escitalopram,26 cases),treatment for 6 weeks.Using the Hamilton Depression Rating Scale(HAMD) and Treatment Emergent Symptom Scale(TESS) to evaluate the efficacy and Side effects.Results:the scores of HAMD reduced significantly after treatment in each group(P<0.01),in the combination group is more obvious.Side effects in two groups have no significant difference(P>0.05).Conclusion:Escitalopram combined with low dose of sulpiride has good curative effect for treatment of depression,fast acting,and mild side effects.
Keywords:Depression  Escitalopram  Shulpiride
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