瘢痕切除即刻局部注射曲安奈德联合放疗治疗耳廓瘢痕疙瘩疗效观察

目的:探讨手术切除,术中曲安奈德局部注射,术后放疗联合治疗耳廓瘢痕疙瘩的效果。方法:将病例分为三组:第一组:12例,24个瘢痕疙瘩(手术+曲安奈德注射+放疗),手术切除瘢痕疙瘩,术中注射醋酸曲安奈德,注射剂量依切缘大小而异,每次注射量不大于40mg,术后每周1次,连续4～8次,术后24h内行局部浅层放疗3天;第二组:11例,22个瘢痕疙瘩(手术+放疗),手术切除瘢痕疙瘩,术后24h内行放疗3天;第三组:17例,23个瘢痕疙瘩(手术+曲安奈德注射),手术切除瘢痕疙瘩,术中即刻注射曲安奈德,术后每周1次,连续4～8次。结果:第一组、第二组、第三组有效率分别为95.83%、77.27%、52.17%。第一组与第二组、第三组比较有显著差异(P<0.05)。结论:手术切除,术中曲安奈德局部注射联合术后放疗治疗耳廓瘢痕疙瘩副作用小、复发率低,值得临床应用。

Clinical application of operation and radiotherapy and triamcinolone acetonid to Cure ear keloid

Objective To investigate the surgical resection,intraoperative triamcinolone acetonide local injection,postoperative radiotherapy combined with the effect of treatment of auricular keloids.Methods The patients were divided into three groups.The first group of 12 patients with 24 keloids(surgery + triamcinolone acetonide injection combined with radiotherapy): surgical removal of keloids,intraoperative injection of triamcinolone acetonide injected dose according to the cutting edge size varies,each injection volume is not greater than 40mg,1 week after surgery,4～ 8 times in a row,24 hours within the local shallow radiotherapy after three days;the second group of 11 patients with 22 keloids(surgery + radiotherapy): Surgical excision of keloids,postoperative 24 hours within three days of radiotherapy;third group of 17 patients with 23 keloids(surgery + triamcinolone acetonide injection): surgical removal of keloids,immediate injection of triamcinolone acetonide,intraoperative and postoperative 1 week,4～8 times in a row.Results: The first group,the second group,third group of the effective rate was 95.83%,77.27%,52.17%.The first group and second group,the third group were significantly different(P <0.05).Conclusion Surgical resection,intraoperative local injection of triamcinolone acetonide,postoperative radiotherapy combined with treatment of auricular keloids side effects,recurrence rate,worthy of clinical application.