| 阿立哌唑与氟哌啶醇治疗抽动障碍的对照研究 |
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| 引用本文： | 陈智敏,雷庆华. 阿立哌唑与氟哌啶醇治疗抽动障碍的对照研究[J]. 中国民康医学, 2012, 24(4): 402+453 |
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| 作者姓名： | 陈智敏 雷庆华 |
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| 作者单位： | 辽宁省复员军人康宁医院,辽宁兴城,125100 |
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| 摘 要： | 目的:比较氟哌啶醇与阿立哌唑治疗抽动障碍的临床疗效和安全性。方法:将62例门诊治疗抽动症患者随机分成两组各31例,分别给予氟哌啶醇和阿立哌唑治疗,疗程8周,在治疗前及治疗后第2、8周末分别采用《耶鲁抽动症整体严重程度量表》(YGTSS)及《副作用量表》(TESS)进行疗效和副反应评估。结果:治疗第2周、第8周末阿立哌唑组和氟哌啶醇组抽动评分明显降低(P<0.05或0.01),阿立哌唑组不良反应比氟哌啶醇组少(P<0.01)。结论:阿立哌唑治疗抽动障碍疗效显著,且安全性高。
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| 关 键 词： | 阿立哌唑 氟哌啶醇 抽动障碍 |
Comparative study of Aripiprazole and Haloperidol in the treatment of tic disorder |
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| CHENG Zhi-min , LEI Qing-hua. Comparative study of Aripiprazole and Haloperidol in the treatment of tic disorder[J]. medical journal of chinese peoples health, 2012, 24(4): 402+453 |
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| Authors: | CHENG Zhi-min LEI Qing-hua |
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| Affiliation: | (The Demobilized Soldiers Kangning Hospital of Liaoning Province,Xincheng 125100,China) |
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| Abstract: | Objective:To compare the clinical efficacy and safety of Aripiprazole and Haloperidol in the treatment of tic disorder.Methods:62 Tourette patients were randomly divided into two groups,treatment with Haloperidol and Aripiprazole for 8 weeks.Before treatment and in the second and eighth weekend,YGTSSS and TESS were used to evaluate efficacy and side effects.Results:In the second and eighth weekend,two group’s tic score decreased significantly(P<0.05or<0.01),Adverse reactions in the Aripiprazole group were less than that in Haloperidol group(P<0.01).Conclusion:Aripiprazole is effective for treatment of tic disorder,and high safety. |
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| Keywords: | Aripiprazole Haloperidol Tic disorder |
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