| 腹膜透析相关性腹膜炎致病菌及耐药性分析 |
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| 引用本文： | 吴晶晶,刘佳,张莉,王珏,邢昌赢. 腹膜透析相关性腹膜炎致病菌及耐药性分析[J]. 中华医院感染学杂志, 2011, 21(16): 3521-3523 |
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| 作者姓名： | 吴晶晶 刘佳 张莉 王珏 邢昌赢 |
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| 作者单位： | 1. 南京医科大学第一附属医院肾内科,江苏,南京,210029
2. 南京医科大学第一附属医院检验科,江苏,南京,210029 |
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| 摘 要： | 目的探讨持续性非卧床腹膜透析(CAPD)相关性腹膜炎的致病菌及其耐药性。方法回顾性分析49例CAPD腹膜炎患者的病原菌、耐药性和转归。结果 31例培养阳性,透出液培养阳性率为63.27%;共培养菌株34株,其中革兰阳性菌22株,革兰阴性菌9株,真菌3株,最常见的病原菌为表皮葡萄球菌和大肠埃希菌;革兰阳性菌对阿米卡星、利奈唑胺、万古霉素、替考拉宁耐药率最低,分别为0、0、4.76%、5.56%,其次为头孢唑林、左氧氟沙星、哌拉西林/他唑巴坦,分别为35.00%、36.36%、37.50%;革兰阴性菌对阿米卡星、亚胺培南耐药率最低,均为0,其次为哌拉西林/他唑巴坦、头孢哌酮/舒巴坦,均为37.50%,对头孢他啶的耐药率为77.78%。结论腹膜透析相关性腹膜炎致病菌仍以革兰阳性菌为主;腹膜炎患者经验治疗可选用哌拉西林/他唑巴坦单一用药;头孢唑林联合头孢哌酮/舒巴坦;左氧氟沙星联合头孢哌酮/舒巴坦;无残存肾功能者可单独选用阿米卡星。
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| 关 键 词： | 腹膜透析 腹膜炎 耐药性 |
Pathogens causing peritoneal dialysis-related peritonitis and their drug resistance |
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| WU Jing-jing,LIU Jia,ZHANG Li,WANG Jue,XING Chang-ying. Pathogens causing peritoneal dialysis-related peritonitis and their drug resistance[J]. Chinese Journal of Nosocomiology, 2011, 21(16): 3521-3523 |
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| Authors: | WU Jing-jing LIU Jia ZHANG Li WANG Jue XING Chang-ying |
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| Affiliation: | WU Jing-jing,LIU Jia,ZHANG Li,WANG Jue,XING Chang-ying(The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China) |
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| Abstract: | OBJECTIVE To investigate the pathogens and their resistance in CAPD-related peritonitis.METHODS Pathogens,resistance and outcomes of 49 cases of CAPD-related peritonitis were analyzed retrospectively.RESULTS Totally 31 cases were cultured positive with a positive rate of 63.27%.A total of 34 strains were cultured,including 22 Gram-positive strains,9 Gram-negative strains and 3 fungi strains.The most common pathogens were Staphylococcus epidermidis and Escherichia coli.Gram-positive bacteria showed lowest re... |
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| Keywords: | Peritoneal dialysis Peritonitis Drug resistance |
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