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NICU医院感染危险因素分析
引用本文:刘兆娥,朱学梅,杨波.NICU医院感染危险因素分析[J].中华医院感染学杂志,2011,21(15):3147-3149.
作者姓名:刘兆娥  朱学梅  杨波
作者单位:1. 山东大学附属省立医院新生儿科,山东,济南,250021
2. 山东大学附属省立医院保健科,山东,济南,250021
摘    要:目的探讨新生儿危重症监护病房(NICU)医院感染的危险因素。方法回顾性调查医院NICU住院患儿临床资料,分析引起医院感染的危险因素。结果医院感染发生率为12.7%;感染部位以呼吸道为主,占54.2%,其次为血液、皮肤软组织,分别占22.4%、8.4%;共培养出病原菌255株,以革兰阴性杆菌为主,占73.7%,以肺炎克雷伯菌最为多见,占14.5%,真菌占5.9%;早产儿、低出生体重儿、暖箱保暖及侵入性操作、全胃肠外营养、抗菌药物应用时间≥2周与医院感染显著相关,共有3个变量进入多元logistic回归方程:胎龄、机械通气≥3 d、抗菌药物应用时间≥2周可作为医院感染发生的独立危险因素。结论 NICU医院感染的危险因素众多,应针对危险因素采取相应的预防措施和对策。

关 键 词:新生儿  新生儿重症监护病房  医院感染  危险因素

Risk factors for nosocomial infections in neonatal intensive care units
LIU Zhao-e,ZHU Xue-mei,YANG Bo.Risk factors for nosocomial infections in neonatal intensive care units[J].Chinese Journal of Nosocomiology,2011,21(15):3147-3149.
Authors:LIU Zhao-e  ZHU Xue-mei  YANG Bo
Institution:LIU Zhao-e,ZHU Xue-mei,YANG Bo(Provincial Hospital Affiliated to Shandong University,Jinan,Shandong 250021,China)
Abstract:OBJECTIVE To describe the epidemiology and risk factors for nosocomial infections(NIs) in neonatal intensive care units(NICU).METHODS A retrospective cohort study was performed.RESULTS The incidence of NIs was 12.7%;the infection sites were respiratory tract(54.2%),followed by blood(22.4%),skin and soft tissues(8.4%).Totally 255 pathogens were isolated,Gram-negative bacillus were dominant(73.7%),of which Klebsiella pneumoniae was the most common pathogenic organisms(14.5%);Fungal infection was 5.9%.Multivar...
Keywords:Neonates  NICU  Nosocomial infections  Risk factors  
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