我国2004年至2009年自体干细胞移植治疗糖尿病足文献计量分析

目的 用文献计量法总结我国2004年至2009年自体干细胞移植(ASCT)治疗糖尿病足的文献,介绍其发展、术式,预测发展趋势等.方法 以"糖尿病足"为检索词,从中文生物医学期刊文献数据库和中国生物医学文献数据库获取题录,再获取原文,按作者、手术方式、刊文期刊、发文机构、地区等行计量分析.结果 共检获104篇,主要发文期刊、发文机构、作者、地区发文数量及术式分别是中国组织工程研究与临床康复杂志(6篇),北京首都医科大学(10篇),谷涌泉(9篇),北京(17篇),手术方式以外周血干细胞移植(ABMSCT)和骨髓干细胞移植(APBSCT)为主.结论 概括性介绍我国发表的ASCT治疗糖尿病足的文献,为深入研究提供了可靠资料.阐述此课题的研究现状并预测主要发展趋势:在严格量化适应证前,ABMSCT及APBSCT为ASCT的主要手术方式;量化ASCT的适应证,与其他药物联用使ASCT更好地发挥作用必将是这一课题的研究热点.

Metrological analysis of literatures on stem cell transplantation for treatment of diabetic foot from 2004 to 2009 in China

Objective To summarize the literature of autologous stem cell transplantation (ASCT) for the treatment of diabetic foot from 2004 to 2009 in China through analyzing its development, the main operative methods as well as the future development tendency. Methods Papers about breast reconstruction from 1987 to 2008 on Chinese Medical Current Content (CMCC) and Chinese Bio-medical Literature Database (CBMdisc) were metrologically analyzed according to journal, institute, operative method, time, content and so on. Results In all 105 papers collected, the first place in terms of journal, institute, author, area, operative method was as follows:Chinese Journal of Clinical Rehabilitation (6 papers), Beijing Capital Medical University (10 papers), Gu Yongquan (9 papers), Beijin (17 papers). Autologous bone marrow stem cell transplantation (ABMSCT) and autologous peripheral blood stem cell transplantation (APBSCT) are the main operative methods. Conclusions This paper provides a credible resource for further study through analyzing papers published in China on stem cell transplantation for treatment of diabetic foot in recent years. ABMSCT and APBSCT must be the main trends in the future. Before formulating strict indications, ABMSCT and APBSCT will be the main operation modes of ASCT. Quantifying indications of ASCT and coupling with other drugs in order to make better role of ASCT will be the main subject of the study.