| 针刺对过敏性哮喘大鼠的影响 |
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| 引用本文： | 崔龙苹 杨永清. 针刺对过敏性哮喘大鼠的影响[J]. 上海针灸杂志, 1999, 18(3): 35-37 |
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| 作者姓名： | 崔龙苹 杨永清 |
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| 作者单位： | 上海市针灸经络研究所 |
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| 基金项目： | 国家自然基金,上海市教委（97C08）资助 |
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| 摘 要： | 目的观察大鼠过敏性哮喘模型肺功能（气道阻力和肺顺应性）、外周血嗜酸粒细胞计数和血清皮质酮水平的变化。方法大鼠过敏性哮喘模型针刺大椎、双肺俞、双风门，以哮喘模型非针刺组哮喘模型捆绑组作为对照组。结果针刺能明显降低大鼠哮喘模型的气道阻力，增加肺顺应性，降低血液嗜酸粒细胞计数，增加皮质酮水平上升。结论针刺对过敏性哮喘至少从降低气道阻力、减少血液嗜酸粒细胞、提高皮质酮水平三个方面发挥其明显的治疗作用，同时也表明针刺与捆绑是两种不同的刺激方式，针刺对过敏性哮喘的治疗不完全依赖糖皮质激素。
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| 关 键 词： | 哮喘／针灸疗法 动物 实验 |
Effects of Acupuncture on Allergic Asthma in SD Rats |
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| Cui Longping Yang Yongqing Chen Hanping Zhang Yingying Ma Shulan Shanghai Research Institute of Acupuncture and Meridian. Effects of Acupuncture on Allergic Asthma in SD Rats[J]. Shanghai Journal of Acupuncture and Moxibustion, 1999, 18(3): 35-37 |
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| Authors: | Cui Longping Yang Yongqing Chen Hanping Zhang Yingying Ma Shulan Shanghai Research Institute of Acupuncture and Meridian |
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| Affiliation: | Cui Longping Yang Yongqing Chen Hanping Zhang Yingying Ma Shulan Shanghai Research Institute of Acupuncture and Meridian,200030 |
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| Abstract: | Objective and Method After acupuncture,lung function(airway resistance and pulmonary compliance),eosinophil counts in peripheral blood and corticosterone in serum were observed with the comparison of blank and restrain groups.Result The results showed that acupuncture significantly decreased airway resistance,increased pulmonary compliance,reduced eosinophil counts in blood and increased corticosterone level in serum compared with that in the control groups.Conclusion The results suggested that acupuncture has therapeutic effects on allergic asthma based on its effects of decreasing airway resistance,reducing eosinophil counts in peripheral blood and increasing corticosterone level in serum.It also showed that acupuncture is a stimulus way which is different from restrain,and the acupunctrue tretment of allergic asthma had no direct relation to corticosteroid. |
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| Keywords: | Asthma/acup mox therapy Animals Laboratory |
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