| 慢性肾功能衰竭患者血清IL-1β、IL-10变化 |
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| 引用本文： | 林淑华,郑烟平,滕舰,袁东,孙芳. 慢性肾功能衰竭患者血清IL-1β、IL-10变化[J]. 中国现代药物应用, 2008, 2(22): 31-32 |
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| 作者姓名： | 林淑华 郑烟平 滕舰 袁东 孙芳 |
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| 作者单位： | 林淑华 (山东省烟台市烟台山医院肾内科,264001)； 郑烟平 (山东省烟台市烟台山医院肾内科,264001)； 滕舰 (山东省烟台市烟台山医院肾内科,264001)； 袁东 (山东省烟台市烟台山医院肾内科,264001)； 孙芳 (山东省烟台市烟台山医院肾内科,264001)； |
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| 摘 要： | 目的探讨血清IL-1β、IL-10在慢性肾功能衰竭患者中的变化及意义。方法30例慢性肾功能衰竭患者及30例健康志愿者进行应用放射免疫法检测血清IL-1β、IL-10水平。结果慢性肾功能衰竭组与正常对照组相比较，血浆IL-1β、IL-10水平均明显高（P〈0．01）。慢性肾功能衰竭组治疗后与治疗前比较，血浆IL-1B水平明显降低、IL-10水平明升高（P〈0．01）。结论IL-1β、IL-10在慢性。肾功能衰竭发生及发展过程中可能起重要作用。
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| 关 键 词： | 慢性肾功能衰竭 IL-1β IL-10 微炎症 |
Changes of Il-1β、Il-10 in Plasma with Chronic Renal Failure |
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| Affiliation: | LIN Shuhua, ZHENG Yanping, TENG Jian et al. (Renal medicine department in Yantaishan Hospital, Yantai, Shandong 264001, China) |
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| Abstract: | Objective To investigate changes of IL-1β and IL-10 in plasma with chronic renal failure. Methods IL-1β and IL-10 in plasma of 30 CRF patients in treatment group and 30 healthy volunteers in normal group were measured by radioimmunity. Result IL-1β and IL-10 in treatment group were higher than those in normal group（P〈0.01）. IL-1βwas lower while IL-10 was higher before treatment than that after in treatment group（P〈0.01）. Conclusion IL-1β and IL-10 are very important in the course of CRF. |
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| Keywords: | IL-10 |
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