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Apatinib as an alternative therapy for advanced hepatocellular carcinoma
Authors:Xi-Hao Zhang  Man-Qing Cao  Xiu-Xiu Li  Ti Zhang
Abstract:Angiogenesis plays an important role in the occurrence and development of tumors. Registered tyrosine kinase inhibitors targeting vascular endothelial growth factor reduce angiogenesis. Apatinib, a tyrosine kinase inhibitor, can specifically inhibit vascular endothelial growth factor receptor 2, showing encouraging anti-tumor effects in a variety of tumors including advanced hepatocellular carcinoma(HCC). This article intends to review the clinical research and application prospects of apatinib in the field of HCC.
Keywords:Apatinib   Hepatocellular carcinoma   Angiogenesis   Vascular endothelial growth factor receptor 2
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点击此处可从《World journal of hepatology》浏览原始摘要信息
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