婴幼儿反复呼吸道感染与佝偻病关系的研究

目的探讨婴幼儿反复呼吸道感染与佝偻病的临床关系。方法回顾性分析反复呼吸道感染的婴幼儿50例作为观察组,对照组为同期健康体检的婴幼儿50名,2组均进行血清钙、磷及骨碱性磷酸酶以及免疫五项含量的检测,分析和比较2组检测结果,观察反复呼吸道感染患儿佝偻病发病率与正常婴幼儿佝偻病发病率的关系。结果观察组血清钙、磷含量均低于对照组（P〈0.05）,骨碱性磷酸酶明显高于对照组（P〈0.01）;观察组免疫五项正常为44例,占88.0%,对照组免疫五项正常为50例,2组比较,具有统计学意义（χ^2=6.387,P〈0.05）;2组患儿佝偻病患病率随着骨碱性磷酸酶的升高而呈上升趋势,二者具有正相关性,2组间比较差异具有统计学意义（P〈0.01）。结论反复呼吸道感染的婴幼儿体内血清钙、磷及骨碱性磷酸酶代谢较紊乱,容易发生佝偻病,佝偻病的患儿由于抵抗力下降,又容易诱发反复呼吸道感染,可见反复呼吸道感染患儿除抗感染等常规治疗外,应常规检测骨碱性磷酸酶,尽早发现、及时治疗佝偻病,否则导致恶性循环。

Research the Relation Between Recurrent Respiratory Infections in Infants With Rickets

Objective To explore relation between recurrent respiratory infections in infants with rickets.Methods Retrospective analysis 50 cases of recurrent respiratory infections in infants to the observe group, during the same period 50 infants of health examination as the control group, 2 sets all carry on the serum calcium, phosphorus,Bone alkaline phosphatase and the immunity five , analysis and comparis the two sets of examination result, observe the relation of the the incidence of rickets in recurrent respiratory infections and young children with normal.Results The observe group, serum calcium, phosphorus is aller low than the control group (P<0.05),the bone alkaline phosphoric is more obviously high than the control group(P<0.01); the observe group the immunity five as normal is 44, have 88%, the control group the immunity five as normal is 50, two group of comparison, the difference between the two groups has a extraordinary statistics to learn meaning(c2=4.43,P<0.05); Two groups of children with rickets Incidence with the increase of bone alkaline phosphatase showed a rising trend, twos have positive relativity, two groups of respectively more the difference have statistics to learn meaning(P<0.05).Conclusion The metabolism of recurrent respiratory infections in infants the serum calcium,phosphorus and bone alkaline phosphatase bone inside the body is disorder, easily lead to rickets disease, Rickets in children due to decreased immunity,They are likely to cause recurrent respiratory tract infections. So, Recurrent respiratory infections in infants,besides the anti- infection treatment, examine Bone alkaline phosphatase in response to the normal regulations, as early as possible detection, cure a rickets disease in time,Otherwise lead to a vicious cycle.