Change in the titers of serum IgG-class autoantibodies to some nervous tissue proteins in patients with life-threatening arrhythmias |
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| Authors: | T. P. Klyushnik E. V. Danilovskaya O. E. Vatolkina M. A. Shkol'nikova V. V. Bereznitskaya A. B. Poletaev N. K. Vabishchevich |
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| Affiliation: | (1) Research Center for Psychic Health, Russian Academy of Medical Sciences, Moscow;(2) Pediatry and Children's Diseases Institute of Ministry of Health, Moscow;(3) Chernobyl' Test Foundation, Moscow |
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| Abstract: | Titers of autoantibodies to nerve growth factor, water-soluble astrocytic protein S-100, glial fibrillary acidic protein, and MP-65 membrane protein of the nervous cell superfamily of integrins was determined by solid-phase immunoenzyme assay in healthy children and in children with the Romano-Ward and sick sinus syndromes. Immunoreactivity to these antigens was either increased or decreased in 20% of sick children in comparison with that of healthy children of the same age. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 677–679, June, 1998 |
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| Keywords: | arrhythmias autoantibodies nerve growth factor neurospecific proteins |
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