| 人乳腺良恶性肿瘤nm23-H1蛋白表达及预后意义 |
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| 引用本文： | 韦义萍,马韵,邓卓霖. 人乳腺良恶性肿瘤nm23-H1蛋白表达及预后意义[J]. 广西医科大学学报, 1999, 16(3): 268-269 |
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| 作者姓名： | 韦义萍 马韵 邓卓霖 |
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| 作者单位： | 1. 广西医科大学附设护士学校,南宁,530021
2. 广西医科大学病理学教研室 |
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| 摘 要： | 目的：探讨ｎｍ２３－Ｈ１蛋白与乳腺上皮性肿瘤的相关性。方法 应用Ｓ－Ｐ免疫组织化学方法检测８１例乳腺良恶性肿瘤组织中ｎｍ２３－Ｈ１蛋白的表达。结果：有淋巴结转移的３９例乳腺癌，ｎｍ２３－Ｈ１生表达率为３３．３％（１３／３９），无淋巴结转移的３１例乳腺癌阳性率为７７．４％（２４／３１），两者差异有非常显著意义（Ｐ〈０．００５）；良性的乳腺导管内乳头状瘤阳民生率为１００％（１１／１１）〉乳腺癌阳性率为
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| 关 键 词： | 乳腺上皮性肿瘤 免疫组化 |
| 修稿时间： | 1998-08-30 |
PROGNOSTIC SIGNIFICANCE OF nm23-H1 PROTEIN EXPRESSION IN BENIGN AND MALIGNANT BREAST TUMORS |
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| Wei Yiping,Ma Yun,Den Zhuolin. PROGNOSTIC SIGNIFICANCE OF nm23-H1 PROTEIN EXPRESSION IN BENIGN AND MALIGNANT BREAST TUMORS[J]. Journal of Guangxi Medical University, 1999, 16(3): 268-269 |
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| Authors: | Wei Yiping Ma Yun Den Zhuolin |
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| Abstract: | Objective: To evaluate the relationship of nm23H1 expression and metastasis of breast neoplasms Methods: 70 cases of human breast carcinomas and 11 cases of intraduatal papilomas were studied by immunohistochemical SP technique,using nm23H1 antibody Results: In the cases of breast carcinoma with or without lymph node metastasis,the nm23H1 positive expression rates were 333%(13/39) and 774%(24/31) respectively,the differences were significant,P<0005The positive rates of benign and malignant were 100% and 529%(37/70),and their differences were also significant,P<001 Conclusion: The results suggest that nm23H1 shows inhibitory effect on the metastasis of breast carcinomaIt may be of great for value clinical prognosis= |
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| Keywords: | nm23-H1 |
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