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实验性急性心肌梗塞时血小板聚集性的变化
引用本文:凌宏,欧阳静萍,卢延芹. 实验性急性心肌梗塞时血小板聚集性的变化[J]. 武汉大学学报(医学版), 1986, 0(2)
作者姓名:凌宏  欧阳静萍  卢延芹
作者单位:湖北医学院病理生理教研室,湖北医学院病理生理教研室,湖北医学院病理生理教研室
摘    要:采用Wu Hoak法测定动脉血中血小板的聚集率,比较家兔实验性急性心肌梗塞前后(AM1组,8只)与急性心肌梗塞并用心得安治疗(治疗组,8只)前后的血小扳聚集率的变化。发现急性心肌梗塞后5h和24h,动脉血中血小板聚集率均明显下降,但心得安治疗组下降程度较AM1组轻(P<0.05)。治疗组梗塞面积也小于AM1组(P<0.01)。

关 键 词:心肌梗塞  血小板聚集  心得安

The Change of platelet Aggregation in Experimental Acute Myocardial Infarction
Ling Hong,et al. The Change of platelet Aggregation in Experimental Acute Myocardial Infarction[J]. Medical Journal of Wuhan University, 1986, 0(2)
Authors:Ling Hong  et al
Abstract:We examined platelet aggregation activity by quantitative analysis of platelet aggregate ratios (Wu Hoak's method) in 16 rabbits, eihgt of which were AMI by ligating left ventricular coronary artery (AMI group), eight of which were AMI and propranolol (0.1mg/kg) treatment (treatment group). After AMI the platelet agreggate ratios in artery blood declined significantly in two groups. The significant differences were noted between the two groups with respect to platelet aggregate ratios and size of myocardial infarction. The platelet aggregate ratios decline significantly in AMI with propranolol less than in AMI, the size of myocardial infarction are smaller.
Keywords:myocardial infarction  platelet aggregation  propranolol
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