益母草注射液联合缩宫素预防剖宫产产后出血及促进子宫复旧的临床研究

目的：探讨益母草注射液联合缩宫素预防剖宫产产后出血及促进术后子宫复旧效果。方法选择孕龄＞28周行剖宫产患者360例，分为治疗组180例，用益母草注射液联合缩宫素治疗；对照组180例，单纯用缩宫素治疗。观察两组产妇术中及术后不同时段出血量、产后出血例数、不同时段子宫收缩情况、子宫复旧情况，较术前血红蛋白下降程度等。结果治疗组各个时段出血量少于对照组，差异有统计学意义（P＜0．05）。治疗组各个时段子宫收缩情况均好于对照组，其中术中、术后2 h、6 h差异有统计学意义（ P＜0．05）。两组术后3 d、5 d子宫底下降幅度比较差异有统计学意义（ P＜0．05）。两组术后48 h与产前血红蛋白下降程度＜1 g／L、1-2 g／L、＞2 g／L比较差异有统计学意义（ P＜0．05）。结论益母草注射液联合缩宫素预防剖宫产产后出血及促进子宫复旧疗效确切，可作为防治产后出血和子宫复旧的优选治疗方案。

Clinical study of the motherwort injection for preventing postpartum hemorrhage and promoting the uterine involution after cesarean section

Objective To evaluate the role of motherwort injection （ yimucao zhusheye ） for preventing post-partum hemorrhage and promoting the uterine involution after cesarean section .Methods There hundred and sixty women at the gestational age of more than 28 weeks who received the cesarean section were divided randomly into the treatment group （ 180 cases ） treated by motherwort injection combined with oxytocin and control group （ 180 cases ） treated by oxytocin .Amount of bleeding during the operation and after operation , the number of cases of postpartum hemorrhage , uterine contraction at different periods ,involution of uterus and hemoglobin decline after operation were observed.Results Amount of bleeding at every period in control group were significantly more than that in treatment group,there were statisticant differences （ P〈0.05 ） .Uterine contraction at different periods in treatment group were all better than that in control group , there were statisticant differences during the operation , at 2 h and 6 h after oper-ation（P〈0.05）.The falling height of the uterus at 3d and 5d between two groups were statisticant differences （P〈0.05 ） .Compared with hemoglobin levels before operation , there were statisticant differences in hemoglobin decrease degree at 〈1 g/L, 1 -2 g/L,〉2g /L（P〈0.05） after operation between two groups .Conclusion Motherwort in-jection combined with oxytocin is useful for preventing postpartum hemorrhage and promoting uterine involution after cesarean section ,which can be used as the preferred treatment for postpartum hemorrhage and uterine contraction .