人与大鼠海马血管构筑的比较性研究

本实验采用血管色素明胶灌注与甲酯铸型扫描电镜法 ,观察比较分析人与大鼠海马血管来源、分布规律及超微结构 ;利用图像分析仪对其血管密度及管径进行测量并分析。结果显示 ,人海马血管来源于大脑后动脉和脉络膜前动脉 ,而大鼠主要来源于大脑后动脉。人海马表面与内部血管呈规律性分布 ,而其内部血管分布不如大鼠明显。大鼠海马血管分布与神经组织构筑相匹配。人与大鼠海马血管内部存在着广泛的血管吻合

A COMPARATIVE STUDY OF HIPPOCAMPAL VASCULATURE IN BOTH HUMAN AND RAT

To comparatively investigate the vascular patterns in the hippocampal formation of both human and rat, the morphology, distribution and origination of hippocampal blood vessels, including both artery and vein were studied by successive injections with India ink and dye. The ultrastructure of the blood vessels was observed by scanning electron microscope with methyl methacrylate vascular replica. Image quantitative analyzer was also used for morphometric comparison of diameters and densities of capillaries in hippocampus. The results showed that the hippocampal arteries arose from the posterior cerebral arteries and anterior choroidal arteries in infants, whereas it mainly stemmed from the posterior cerebral arteries in rats. The blood vessels on hippocampal surface and internal angioarchitecture were regularly arranged in human, however the internal angioarchitecture was not as obvious as in rats. These results have demonstrated a close relationship between the microangioarchitecture and the arrangement of nervous tissue in hippocampus of rats, and there are lots of microvascular anastomoses and capillary networks in the hippocampus in both human and rat.