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A case of a placental site trophoblastic tumor
Authors:Fujihiko Suzuki  Akira Saito  Kazuhisa Ishii  Akihiko Yamamura  Michio Matsumoto  Masanobu Eguchi  Masataka Tanno  Kunio Mizuguchi  Yoshinori Hosokawa  Koichi Suda  Sachiko Takase
Affiliation:1. Clinical Laboratory, Juntendo University School of Medicine, Urayasu Hospital, 2-1-1, Tomioka, 279, Urayasu, Japan
2. Department of Pathology, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, 113, Tokyo, Japan
3. Department of Obstetrics and Gynecology, Katsunan Hospital, 3-4-32, Toudaijima, 279, Urayasu, Japan
Abstract:A rare placental site trophoblastic tumor (PSTT) in a 39-year-old female was studied. This tumor, protruding into the uterine cavity, was histologically similar to tumors in previously reported cases of PSTT. Ultrastructurally, the characteristic finding was the presence of perinuclear filaments. Also, the tumor cells were strongly positive for hPL by immunohistochemical method. These findings suggest that this was a tumor caused by neoplastic proliferation of the extravillous intermediate trophoblast.
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