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重组人血小板生成素促进异基因造血干细胞移植血小板恢复的随机对照临床试验
引用本文:江岷,潘欣,徐晨,陈健琳,杨帆,楼晓,张伟沂,李欲航,宁红梅,李渤涛,胡亮钉,任婧,俞志勇,王庆含,陈虎. 重组人血小板生成素促进异基因造血干细胞移植血小板恢复的随机对照临床试验[J]. 血栓与止血学, 2011, 17(6): 247-253
作者姓名:江岷  潘欣  徐晨  陈健琳  杨帆  楼晓  张伟沂  李欲航  宁红梅  李渤涛  胡亮钉  任婧  俞志勇  王庆含  陈虎
作者单位:军事医学科学院附属医院造血干细胞移植中心,北京,100071
摘    要:目的 评价重组人血小板生成素(rhTPO)在异基因造血干细胞移植中促进血小板恢复的临床有效性和移植安全性.方法 123例接受标准骨髓清除性预处理方案的HLA相合同胞及无血缘造血干细胞移植受者,随机进入试验组(n=61)和对照组(n=62).试验组第7天开始接受rhTPO 1.0 μg/kg·d-皮下注射,至第20天或虽...

关 键 词:重组人血小板生成素  造血干细胞移植  疗效  不良反应

Recombinant Human Thrombopoietin Improves Platelet Recovery after Allogeneic Hematopoietic Stem Cell Transplantation: A Randomized, Controlled Clinical Trial
JIANG Min,PAN Xin,XU Chen,CHEN Jian-lin,YANG Fan,LOU Xiao,ZHANG Wei-yi,LI Yu-hong,NING Hong-mei,LI Bo-tao,HU Liang-ding,REN Jing,YU Zhi-yong,WANG Qing-han,CHEN Hu. Recombinant Human Thrombopoietin Improves Platelet Recovery after Allogeneic Hematopoietic Stem Cell Transplantation: A Randomized, Controlled Clinical Trial[J]. Chinese Journal of Thrombosis and Hemostasis, 2011, 17(6): 247-253
Authors:JIANG Min  PAN Xin  XU Chen  CHEN Jian-lin  YANG Fan  LOU Xiao  ZHANG Wei-yi  LI Yu-hong  NING Hong-mei  LI Bo-tao  HU Liang-ding  REN Jing  YU Zhi-yong  WANG Qing-han  CHEN Hu
Affiliation:JIANG Min,PAN Xin,XU Chen,CHEN Jian-lin,YANG Fan,LOU Xiao,ZHANG Wei-yi,LI Yu-hong NING Hong-mei,LI Bo-tao,HU Liang-ding,REN Jing,YU Zhi-yong,WANG Qing-han,CHEN Hu(Department of Hematopoietic Stem Cell Transplantation,Affiliated Hospital to Academy of Military Medical Sciences,Beijing,100071,China)
Abstract:
Keywords:Recombinant humanized thrombopietin(rhTPO)  Hematopoietic stem cell transplantation(HSCT)  Response  Adverse events  
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