| 纤维瘤病的临床病理和免疫组化分析 |
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| 引用本文： | 周祖平,李卉.纤维瘤病的临床病理和免疫组化分析[J].临床与实验病理学杂志,1998,14(5):470-471,I061. |
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| 作者姓名： | 周祖平 李卉 |
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| 作者单位： | [1]山东淄博矿务局中心医院病理科 [2]山东省淄博市淄川区人民医院病理科 |
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| 摘 要： | 目的：探讨纤维瘤病的组织发生和临床病理特征。方法：对１６例手术切除的纤维病标本进行了光镜观察和免疫组织化学ＬＳＡＢ法染色，结果；腹壁及腹壁外的纤维瘤病表达ＡＳＭＡ和Ｓ－１００蛋白，Ｓ－１００蛋白阳性细胞呈散在分布，复发的２例ＰＣＮＡ呈弱阳性，肿瘤的主要成分为肌纤维母细胞，可以见到Ｓ－１００阳性表达。结论：纤维瘤病率来源皇多潜能的间叶细胞。
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| 关 键 词： | 纤维瘤 病理形态 免疫组织化学 |
A clinicopathological and immunohistochemical study of fibromatosis |
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| Zhou Zuping,Li Hui,Hu Baoyun,et al.A clinicopathological and immunohistochemical study of fibromatosis[J].Chinese Journal of Clinical and Experimental Pathology,1998,14(5):470-471,I061. |
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| Authors: | Zhou Zuping Li Hui Hu Baoyun |
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| Institution: | 1Zhou Zuping,2Li Hui,1Hu Baoyun,et al |
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| Abstract: | Purpose To investigate the histogenesis and clinicopathological characteristics of fibromatosis. Methods Sixteen cases of fibromatosis were studied by light microscope and immunohistochemical (LSAB method). Results The extraabdominal and abdominal fibromatosis showed alpha smooth muscle actin or S 100 expression, neurilemmal cell in tumor tissues was scattered distribution, two cases of recurrence was weak for PCNA,the tumor was major composed of myofibroblast. It was found that the fibromatosis was differentiating into neurilemmal cell and synovium fissure. Conclusion The fibromatosis is originated from the primitive nucommited mesenchyme. |
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| Keywords: | fibromatosis pathomorphology immunohistochemistry |
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