| 咖啡因诱发人类染色体脆性部位的观察 |
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| 引用本文： | 张红恩.咖啡因诱发人类染色体脆性部位的观察[J].中南大学学报(医学版),1988(2). |
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| 作者姓名： | 张红恩 |
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| 作者单位： | 湖南医学院医学遗传学研究室 |
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| 摘 要： | 观察了咖啡因对14名个体染色体脆性部位的影响。结果表明咖啡因可显著地提高染色体结构畸变率和染色体脆性部位的表达。对有关的问题进行了论讨。
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| 关 键 词： | 染色体 人 染色体脆弱位点 染色体畸变 咖啡因 |
COMMON FRAGILE SITES OF HOMAN CHROMOSOME INDUCED BY CAFFEINE TREATMENT |
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| Zhang Hongen.COMMON FRAGILE SITES OF HOMAN CHROMOSOME INDUCED BY CAFFEINE TREATMENT[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1988(2). |
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| Authors: | Zhang Hongen |
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| Institution: | Zhang Hongen Department of Medical Genetics |
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| Abstract: | Common fragile sites of human chromosome of peripheral blood cells with and without caffeine treatment in 14 individuals were analyzed. The result showed that 1. individual difference in chromosome structural aberration rate was present, 2. caffeine could significantly enhance the expression of common fragile sites, and 3. there was a correlation between chromosome structual aberration rate with and without caffeine treatment. Some questions related to common fragile sites were discussed. |
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| Keywords: | Chromosomes human Chromosome fragile sites Chromosome aberrations Caffeine |
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