Exercise training without ventricular remodeling in patients with moderate to severe left ventricular dysfunction early after acute myocardial infarction |
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| Authors: | Otsuka Yoritaka Takaki Hiroshi Okano Yoshiaki Satoh Toru Aihara Naohiko Matsumoto Takahiro Yasumura Yoshio Morii Isao Goto Yoichi |
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| Affiliation: | Department of Medicine, Division of Cardiology, National Cardiovascular Center, Fujishirodai 5-7-1, Suita, 565-8565, Osaka, Japan. |
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| Abstract: | BACKGROUND: The purpose of this study was to determine whether or not patients with moderate to severe left ventricular (LV) dysfunction benefit from exercise training starting early after acute myocardial infarction (AMI) without deteriorating LV remodeling. METHODS: We investigated changes in exercise capacity and LV end-diastolic dimension (LVDd by two-dimensional echocardiography) before and after exercise training in 126 patients after AMI. Patients were divided into three groups according to LV ejection fraction (EF) at the beginning of exercise training: 74 patients with LVEF>/=45% (Group H), 35 patients with 35%
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