| 旋光法测定硫酸阿米卡星注射液含量 |
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| 引用本文： | 陈怡,李玉兰,何丽芳. 旋光法测定硫酸阿米卡星注射液含量[J]. 天津药学, 2004, 16(5): 26-27 |
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| 作者姓名： | 陈怡 李玉兰 何丽芳 |
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| 作者单位： | 1. 广东省深圳市药品检验所,深圳,518029
2. 广东省深圳职业技术学院,深圳,518029 |
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| 摘 要： | 目的 :建立硫酸阿米卡星注射液含量测定方法。方法 :以水为溶剂 ,运用旋光法测定硫酸阿米卡星注射液含量。结果 :阿米卡星在 1～ 2 0 mg/ml范围内浓度与旋光度呈良好线性关系 ,回归方程 :C =7.892 7A - 0 .0 35 5 ,r =0 .9999,平均回收率 99.8% ,RSD为 0 .89% (n =5 )。结论 :本法简便易行 ,结果准确 ,可作为该制剂的质控方法
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| 关 键 词： | 旋光法 硫酸阿米卡星 含量测定 |
| 文章编号： | 1006-5687(2004)05-0026-02 |
| 修稿时间： | 2004-04-12 |
Determination of the content of amikacin sulfate injection by polarimetric analysis |
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| Chen Yi,Li Yulan,He Lifang. Determination of the content of amikacin sulfate injection by polarimetric analysis[J]. Tianjin Pharmacy, 2004, 16(5): 26-27 |
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| Authors: | Chen Yi Li Yulan He Lifang |
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| Affiliation: | Chen Yi1,Li Yulan1,He Lifang2 |
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| Abstract: | Object: To establish a method for determining the content of amikacin sulfate injection. Methods: Polarimetric analysis was used and water as solvent. Results: The linear range of amikacin was 1~20 mg/ml. The regression equation was: C=7.892 7 A-0.035 5(r=0.999 9). The average recovery was 99.8% with the RSD of 0.89 %. Conclusion: The method was convenient, accurate and reliable. It was therefore suitable for the quality control of amikacin sulfate injection. |
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| Keywords: | polarimetry amikacin sulfate determination |
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