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松塔化学成分的研究
引用本文:杨鑫,丁怡,孙志浩,张东明. 松塔化学成分的研究[J]. 药学学报, 2005, 40(5): 435-437
作者姓名:杨鑫  丁怡  孙志浩  张东明
作者单位:1. 江南大学,生物工程学院,江苏,无锡,214036
2. 中国医学科学院、中国协和医科大学药物研究所,北京,100050
基金项目:国家自然科学基金资助项目(20432030)
摘    要:目的研究华山松松塔的化学成分。方法用溶剂法和色谱法分离化合物,波谱法鉴定其结构。结果 分离得到4个二萜类化合物,其结构鉴定为7-oxo-12α,13β-dihydroxyabiet-8(14)-en-18-oic acid (I), 7-oxo-13β-hydroxyabiet-8(14)-en-18-oic acid (II), 8(14)-podocarpen-13-on-18-oic acid (III)和lambertianic acid (IV)。结论I为新化合物,其结构鉴定为7-oxo-12α,13β-dihydroxyabiet-8(14)-en-18-oic acid,化合物II,III为首次从该植物中分离得到。

关 键 词:华山松  松塔  化学成分
收稿时间:2004-10-20

Studies on chemical constituents of Pinus armandii
YANG Xin,DING Yi,SUN Zhi-hao,ZHANG Dong-ming. Studies on chemical constituents of Pinus armandii[J]. Acta pharmaceutica Sinica, 2005, 40(5): 435-437
Authors:YANG Xin  DING Yi  SUN Zhi-hao  ZHANG Dong-ming
Affiliation:School of Bioengineering, Southern Yangtze University, Wuxi 214036, China.
Abstract:AIM: To study chemical constituents from pine cone of Pinus armandii Franch. METHODS: The constituents were isolated by chromatographic method and the structures were identified on the basis of spectral analysis. RESULTS: Four compounds were identified as 7-oxo-12alpha, 13beta-dihydroxyabiet-8(14)-en18-oic acid (I), 7-oxo-13beta-hydroxyabiet-8 (14)-en-18-oic acid (II), 8 (14)-podocarpen-13-on-18-oic acid (III) and lambertianic acid (IV). CONCLUSION: Compound I is a new diterpenoid and compounds II, III were isolated from this plant for the first time.
Keywords:Pinus armandii Franch  pine cone  chemical constituents
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