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血清透明质酸与层粘连蛋白的联合检测在急、慢性肝病中的作用
引用本文:邹琳,李青莉,阙英男.血清透明质酸与层粘连蛋白的联合检测在急、慢性肝病中的作用[J].实用临床医学(江西),2006,7(10):32-32,35.
作者姓名:邹琳  李青莉  阙英男
作者单位:江西省人民医院核医学科,江西南昌330006
摘    要:目的:探测血清透明质酸(HA)与层粘连蛋白(LN)的联合检测在急、慢性肝病中的作用。方法:采用放射免疫法测定正常对照组18例及急、慢性肝病患者76例HA、LN的含量,结果76例急、慢性肝病患者血清HA、LN与正常对照比较,差异有显著性(P〈0.01)。结论:以HA、LN为实验参考指标,对尽早发现慢性肝病向肝硬化转化起到早预防、早诊治的作用。

关 键 词:透明质酸  层粘连蛋白  急性肝炎  慢性肝炎  肝硬变
文章编号:1009-8194(2006)10-0032-01
收稿时间:07 26 2006 12:00AM
修稿时间:2006-07-26

Examination of Serum HA and LN in Acute and Chronic Liver Diseases
Zou Lin, Li Qing-Li ,Jue ying-nan.Examination of Serum HA and LN in Acute and Chronic Liver Diseases[J].Practical Clinical Medicine,2006,7(10):32-32,35.
Authors:Zou Lin  Li Qing-Li  Jue ying-nan
Abstract:Objective:To evaluate the effect of examination of serum HA and LN in acute and chronic liver diseases. Methods: Serum concentration of HA and LN were measured by RIA in blood specimens obtained from the patients with acute and chronic liver diseases and 18 normal controls. Results: For concentration of serum HA and LN, compared acute and chronic liver diseases with normal control group, there were significant differences(P<0.01). Conclusion: The measurement of concentration of serum HA and LN play a important role in discovering the development from chronic liver disease to liver cirrhosis as early as possible so as to early prevention and therapy.
Keywords:hyaluronicacid  laminin  acute hepatilis  chronic hepatitis  liver cirrhosis
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