Cytotoxicity of three resin-based root canal sealers: an in vitro evaluation |
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| Authors: | E. A. Koulaouzidou K. . Papazisis P. Beltes G. D. Geromicholos A. H. Kortsarls |
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| Affiliation: | Department of Endodontology, Dental School, Aristotle University;Department of Virology and Tissue Culture, Theagenion Cancer Institute, Thessaloniki, Greece |
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| Abstract: | Abstract— The cytotoxicity of three resin-based root canal sealers (AH26, AH-Plus, Topseal) was evaluated in vitro. The experiments included two cell lines, L929 mouse skin fibroblasts and RPC-C2A rat pulp cells. The cytotoxicity was assessed by sulforodamine B (SRB) colorimetric assay and hemocytometer viable cell counting after 24- and 48-h exposure. AH26 had a severe cytotoxic effect whilst Topseal and AH-Plus showed a markedly lower toxic influence on the cells during the experimental period. |
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| Keywords: | endodontic materials material toxicity: root canal sealers |
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