| RNA干扰技术治疗妇科恶性肿瘤 |
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| 引用本文： | 冯坤（综述）,周怀君（审校）. RNA干扰技术治疗妇科恶性肿瘤[J]. 国外医学:妇产科学分册, 2009, 0(5): 371-372,390 |
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| 作者姓名： | 冯坤（综述） 周怀君（审校） |
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| 作者单位： | [1]南京中医药大学中西医结合鼓楼医学院,210029 [2]南京市鼓楼医院,210029 |
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| 摘 要： | RNA干扰（RNAi）是双链RNA诱导细胞内特定基因沉默的现象。随着对RNAi技术研究的不断深入,其作用机制正在被逐步阐明,RNAi技术也日趋完善和成熟,已广泛应用于许多研究领域,如功能基因学,微生物学,基因表达调控机制研究等领域。在肿瘤方面,更取得突破性进展,为肿瘤的基因治疗开辟了新的有效途径。就RNAi技术在妇科恶性肿瘤方面的应用进展综述。
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| 关 键 词： | RNA干扰 宫颈癌 卵巢癌 子宫内膜癌 |
The Research of RNA Interference in the Treatment of Gynecological Malignant Tumor |
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| Affiliation: | FENG Kun, ZHOU Huai-jun. (1 Gulou Clinical Medical College of Integrative Chinese-western Medicine, The No.1 Clinical Medical College, Nnnjing University of Chinese Medicine, Nanjing 210029, China;2 The Drum Tower Hospital, Nanjing 210008, China) |
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| Abstract: | RNA interference （RNAi） is a post-transportational gene silencing induced by introduction of double-stranded RNA. With the deepening study of RNAi technology, its mechanism is being clarified gradually. RNAi technology is also becoming more perfect and mature, and has been widely used in many research areas, such as functional genome, microbiology and regulatory mechanism of gene expression. And a breakthrough has been made in the field of tumor therapy. So it has opened a new effective way in tumor area. This article will provide a review on the application of RNAi technology on gynecologic malignant. |
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| Keywords: | RNA interference Cervical cancer Ovarian cancer Endometrial cancer |
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