人抗IgG抗体上的交叉反应性独特型 |
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作者姓名: | Carson、D.A Chen P.P Jirik F Goldflen R Fong.S 黄其全 |
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作者单位: | Department of Basic and Clinical Research,Scripps Clinic and Research Foudation,La Jolla,California,92037,Department of Basic and Clinical Research,Scripps Clinic and Research Foudation,La Jolla,California,92037,Department of Basic and Clinical Research,Scripps Clinic and Research Foudation,La Jolla,California,92037,Department of Basic and Clinical Research,Scripps Clinic and Research Foudation,La Jolla,California,92037,Department of Basic and Clinical Research,Scripps Clinic and Research Foudation,La Jolla,California,92037 |
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摘 要: | 在类风湿性关节炎和Siogren's综合症患者体内已确定存在高滴度的抗-IgG抗体(类风湿因子,RF),并可能与免疫复合物的形成和组织损伤有关。但在许多正常人血清中也发现了RF。有关在正常和病理状态下RF自身抗体合成的遗传基础仍未确定。为了搞清在许多无
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