尿毒症继发不安腿综合征73例临床表现分析

目的 了解尿毒症继发不安腿综合征患者患病率、严重程度、危险因素、具体不适部位及临床表现.方法 以2015年3～7月于首都医科大学附属北京友谊医院、北京第六医院、北京中兴医院、首都医科大学附属北京朝阳医院血液净化中心尿毒症持续性血液透析患者186例为研究对象,进行横断面研究,采用床旁问卷形式,以国际不安腿综合征研究小组(...

Clinical analysis of 73 cases of restless legs syndrome in uremic patients

Objective To investigate the prevalence,severity,risk factors,specific discomfort sites and clinical manifestations of restless leg syndrome(RLS)in uremic patients.Methods One hundred and eighty-six cases of continuous hemodialysis patients with uremia in Beijing Friendship Hospital,Capital Medical University,Beijing Sixth Hospital,Beijing Zhongxing Hospital,and Beijing Chaoyang Hospital Blood Purification Center from March to July 2015 were investigated by face-to-face interviews.The study subjects were used cross-sectional studies,bedside questionnaires,diagnosed according to the 4 basic criteria established by the International Restless Legs Syndrome Research Group(IRLSS),and graded according to the severity of the IRLSSG scale,and the patient's general condition,living habits,treatment status and related laboratory examinations were counted,and the patient's discomfort parts and specific clinical manifestations were recorded.Results 186 patients were enrolled,and they were divided into RLS(+)group of 73 cases and RLS(-)group of 113 cases according to whether they met the RLS diagnosis.RLS(+)group:the prevalence rate was 39.25%,the IRLSSG scores of the patients were(16.44±7.36)scores,68.50% patients were above moderate.Compared with the RLS(-)group,RLS(+)group had more kidney transplantation failure surgeries(42/31 vs.44/69),few Iron drugs(28/45 vs.61/52),and few hemofiltration therapies(51/22 vs.96/17),with significant differences(P<0.05).Among the patients with RLS(+)group,89.04% patients were involved in both lower limbs,5.48% in unilateral lower limbs,2.74% in both upper limbs,and 2.74% in limbs.Muscle discomfort accounted for 80.82% of all patients,and surface discomfort for 8.22%.Conclusion RLS in uremia patients is associated with kidney transplantation failure,no application of iron and hemofiltration.RLS mainly involved lower limbs,mainly involved internal muscle discomfort.