高血压病合并冠心病患者中医证型分布特征与危险因素分析

目的 探索高血压病合并冠心病中医证型分布特征与危险因素.方法 回顾性分析我院762例高血压患者病历资料,并按是否合并冠心病进行分组,记录各组患者一般资料与实验室检测指标,应用χ2检验、秩和检验与Logistic回归等统计学方法对其中医证型分布规律与危险因素进行分析.结果 高血压合并冠心病的中医证型以阴虚阳亢、瘀血阻络为...

Analysis of Distribution Characteristics of Traditional Chinese Medicine Syndrome Types in Patients with Hypertension Combined with Coronary Heart Disease and Risk Factors

Objective To explore the distribution characteristics of traditional Chinese medicine(TCM)syndrome types of hypertension combined with coronary heart disease and its possible risk factors.Methods The data of 762 patients with hypertension in our hospital were analyzed retrospectively.The patients were divided into groups according to whether they were combined with coronary heart disease or not.The general data and laboratory test indexes of each group were recorded.The distribution of TCM syndrome types and risk factors were analyzed by chi-square,rank sum test and Logistic regression.Results The TCM syndromes of hypertension with coronary heart disease were mainly Yin deficiency and Yang hyperactivity,blood stasis and collaterals obstruction.Multivariate Logistic regression results showed that age,body mass index(>24 kg/m^2),smoking history,diabetes history,high blood uric acid,high blood homocysteine(Hcy),high mean platelet volume(MPV)and high width of platelet volume distribution(PDW)were risk factors for hypertension patients with coronary heart disease,and high density lipoprotein cholesterol(HDL-C)was the protective factor,among them,low density lipoprotein cholesterol(LDL-C)level was also a protective factor for the occurrence of syndrome of Yin deficiency and Yang hyperactivity,Hcy was a risk factor for the occurrence of syndrome of Yin deficiency and Yang hyperactivity,and smoking history,MPV and PDW were risk factors for the occurrence of syndrome of blood stasis.Conclusion The main pathogenesis of hypertension combined with coronary heart disease is Yin deficiency and Yang hyperactivity,blood stasis and collaterals obstruction;reduce smoking(especially the elderly patients with hypertension),maintain normal body mass,and regularly monitor indexes such as creatinine,blood uric acid and Hcy can reduce the risk of hypertension combined with coronary heart disease.