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放疗联合免疫检查点抑制剂治疗非小细胞肺癌的研究进展
引用本文:康岩,王鑫. 放疗联合免疫检查点抑制剂治疗非小细胞肺癌的研究进展[J]. 现代肿瘤医学, 2021, 0(4): 708-712. DOI: 10.3969/j.issn.1672-4992.2021.04.038
作者姓名:康岩  王鑫
作者单位:1.北京市房山区良乡医院肿瘤科,北京 102401;2.国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京 100021
基金项目:北京市房山区良乡医院院内基金(编号:2017-04)。
摘    要:肺癌是世界范围发病率和死亡率最高的恶性肿瘤,非小细胞肺癌(non-small cell lung cancer,NSCLC)约占85%,其中30%~40%的患者确诊时为局部晚期,40%的患者为转移性肺癌.肺癌的治疗需要采用综合治疗手段,放疗作为传统治疗手段之一,在各期肺癌的治疗中发挥着重要作用.免疫检查点抑制剂(imm...

关 键 词:非小细胞肺癌  放射治疗  免疫检查点抑制剂

Advances in radiotherapy combined with immune checkpoint inhibitors in the treatment of non-small cell lung cancer
KANG Yan,WANG Xin. Advances in radiotherapy combined with immune checkpoint inhibitors in the treatment of non-small cell lung cancer[J]. Journal of Modern Oncology, 2021, 0(4): 708-712. DOI: 10.3969/j.issn.1672-4992.2021.04.038
Authors:KANG Yan  WANG Xin
Affiliation:1.Department of Oncology,Liangxiang Hospital of Beijing,Beijing 102401,China;2.Department of Radiotherapy,Cancer Hospital Chinese Academy of Medical Sciences,Beijing 100021,China.
Abstract:Lung cancer is a malignant tumor with the highest morbidity and mortality in the world.85%of lung cancer are non-small cell lung cancer(NSCLC),30%~40%of which are local advanced NSCLC at the time of diagnosis and 40%are metastasis disease.The comprehensive protocol is essential for NSCLC,and radiotherapy is one of the traditional methods playing a very important role in all stages of NSCLC.With the development of immune checkpoint inhibitors(ICIs),the therapeutic strategy for NSCLC is changing gradually.The synergistic effect of radiotherapy and immunotherapywould improve the prognosis of NSCLC.This article reviews the researchprogress of radiotherapy combined with ICIs in the treatment of NSCLC.
Keywords:non-small cell lung cancer  radiotherapy  immune checkpoint inhibitors
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