全子宫切除和次全子宫切除对卵巢功能远期影响的研究

目的探讨子宫肌瘤患者行全子宫切除术与次全子宫切除术对卵巢功能的远期影响。方法选择2003年1～2月于江苏省海安县人民医院妇科病区行子宫切除的子宫肌瘤患者43例,其中全子宫切除患者20例,年龄35～42岁,平均3±72.18岁。次全子宫切除患者23例,年龄33～42岁,平均年龄3±72.84岁。在患者术后3年即2006年1～2月测定性激素FSH、LH、E2值,并选择同期在妇科门诊就诊阴道炎症患者测定其性激素FSH、LH、E2值15例作为对照。对所有手术组及对照组患者均采用问卷形式调查有无围绝经期综合征的发生。结果全子宫切除组和次全子宫切除组患者之间相比,术后3年FSH、LH、E2值差异均没有显著性,P〉0.05。手术组术后3年和对照组FSH、LH、E2各两两比较差别均有显著性差异,P〈0.05。全子宫切除、次全子宫切除、对照组患者围绝经期综合征发生率分别为40%、21.7%、6.67%,三组两两比较,全子宫切除患者与对照组有统计学意义,P〈0.05。结论子宫切除术后3年患者卵巢功能较正常有所减退,全子宫切除与次全子宫切除两组间并无差异,但全子宫切除术术后3年围绝经期综合征发生率升高。

The study of the influence on long-term ovarian function treated by total and subtotal hysterectomy

Objective To explore influence of total and subtotal hysterectomy on long-term ovarian function of women who had suffered from uterine tumor. Methods 43 women with uterine tumor were studied in Jiangsu Hal＇ an People＇ s Hospital from January to February in 2001,20 of them having undergone total hysterectomy and 23 subtotal hysterectomy. And total hysterectomy the patient 20 examples, average age 35 -42 years old. ; subtotal hysterectomy the patient 23 examples, average age 33 - 42 years old. Their hormone （ LH, FSH, and E2 ） level in blood was tested three years after operation. The hormone （ LH, FSH, and E2 ） level in blood of another 15 women with colpitis who were treated in the women＇ s outpatient in the same＇s period was tested. Resuits There is no great difference between LH, FSH and E2 of patients having been undergone total hysterecto- my and that of those having been undergone subtotal hysterectomy three years after operation （ P 〉 0. 05 ）. The patients having been undergone total and subtotal hysterectomy three years after operation were found a great difference between their hormone （ LH, FSH, and E2 ） level and that of women without uterine tumor （ P 〈 0.05 ）. The formation rate on encicles menopause syndrome of those undergoing total and subtotal hysterectomy and the control group respectively is 40% ,21.7% ,6. 67%. The formation rate on encicles menopause syndrome of those undergoing total hysterectomy and the control group respectively have statistics significiance （P 〈 0. 05 ）. Conclusion The ovarian function of women undergoing hysterectomy three years after operation is lower than that of women without uterine tumor. There is indifference between those undergoing total hysterectomy and subtotal hysterectomy three years after operation, but the formation rate on encicles menopause syndrome of those undergoing total hysterectomy is higher .