| 青春期PCOS患者血清C反应蛋白水平的变化及意义 |
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| 引用本文： | 侯灵彤,郑桓,高鹰. 青春期PCOS患者血清C反应蛋白水平的变化及意义[J]. 山东医药, 2008, 48(12): 4-6 |
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| 作者姓名： | 侯灵彤 郑桓 高鹰 |
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| 作者单位： | 华北煤炭医学院附属医院,河北唐山,063000;华北煤炭医学院附属医院,河北唐山,063000;华北煤炭医学院附属医院,河北唐山,063000 |
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| 摘 要： | 目的 探讨青春期多囊性卵巢综合征(PCOS)患者血清C 反应蛋白(CRP)水平的变化及其意义.方法 对26 例青春期PCOS患者(研究组)及20例正常青春期对照者(对照组)进行血清CRP及性激素检测,同时进行葡萄糖耐量试验(OGTT)及胰岛素(INS)释放试验.计算体质量指数(BMI)、空腹血糖胰岛素比率(FGIR)、糖负荷120 min血糖胰岛素比率(G120/I120)及稳态模型的胰岛素抵抗指数(HOMA-IR).结果 研究组血清T水平及LH/FSH比值、logCRP均明显高于对照组(P均＜0.05);研究组BMI、空腹INS及OGTT后血糖、INS、HOMA-IR均明显高于对照组(P均＜0.05),而FGIR及G120/I120均明显低于对照组(P均＜0.05);Pearson相关分析显示,logCRP与BMI、HOMA-IR呈正相关(r=0.37,P均＜0.05);排除BMI影响后的偏相关分析显示,logCRP与HOMA-IR仍呈正相关(r=0.28,P均＜0.05),与FGIR及G120/I120呈负相关(r分别为-0.32、-0.29,P均＜0.05).结论 合并IR的青春期PCOS患者血清CRP水平升高.
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| 关 键 词： | 多囊卵巢综合征 青春期 C-反应蛋白 炎症 胰岛素抵抗 |
| 文章编号： | 1002-266X(2008)12-0004-03 |
Significance of Sermn C-reactive protein change in adolescence women with polycystic ovary syndrome |
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| HOU Ling-tong,ZHENG Huan,GAO Ying. Significance of Sermn C-reactive protein change in adolescence women with polycystic ovary syndrome[J]. Shandong Medical Journal, 2008, 48(12): 4-6 |
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| Authors: | HOU Ling-tong ZHENG Huan GAO Ying |
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| Affiliation: | HOU Ling-tong,ZHENG Huan,GAO Ying(1Affiliated Hospital of North China Coal Medical College,Tangshan 063000,P.R.China) |
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| Abstract: | Objective To investigate the expression and significance of sermn C-reactive protein(CRP) in adolescence women with polycystic ovary syndrome(PCOS).Methods 26 adolescence women with PCOS(test group) and 20 ovulating healthy adolescence women(controls group) were recruited.Serum CRP,sex hormone concentration,oral glucose tolerance tests(OGTT) and insulin release tests(IRT) were tested in all cases.Body mass index(BMI),Fasting glucose to insulin ratio(FGIR),2-hour glucose to insulin ratio(G120/I120) and Homeo... |
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| Keywords: | polycystic ovary syndrome C-reactive protein adolescence inflammation insulin resistance |
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