| 光合细菌生物转化技术在中药研究中的应用进展 |
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| 引用本文： | 牛红军,李邦东,李军,李建文,杨官娥.光合细菌生物转化技术在中药研究中的应用进展[J].中草药,2014,45(13):1966-1970. |
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| 作者姓名： | 牛红军 李邦东 李军 李建文 杨官娥 |
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| 作者单位： | 天津现代职业技术学院, 天津 300350;哈药集团生物工程有限公司, 黑龙江 哈尔滨 150025;山西医科大学药学院, 山西 太原 030001;山西医科大学药学院, 山西 太原 030001;山西医科大学药学院, 山西 太原 030001 |
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| 基金项目： | 国家自然科学基金资助项目（30672621，81173473）；山西省自然科学基金资助项目（2010011048-2）；山西医科大学青年基金资助项目（02201124，02201128）；天津现代职业技术学院科研课题（201417） |
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| 摘 要： | 微生物转化技术在中药研究中的应用越来越广泛，利用光合细菌对中药进行生物转化处理已成为微生物转化领域的研究热点之一。搜集光合细菌生物转化中药相关研究文献，综述了光合细菌转化中药的药理药效学、药效物质基础和转化机制，并指出有待进一步研究的问题。
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| 关 键 词： | 光合细菌 生物转化 中药 药效物质基础 微生物转化 |
| 收稿时间： | 2014/1/27 0:00:00 |
Application of photosynthetic bacteria biotransformation in research of Chinese materia medica |
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| NIU Hong-jun,LI Bang-dong,LI Jun,LI Jian-wen and YANG Guan-e.Application of photosynthetic bacteria biotransformation in research of Chinese materia medica[J].Chinese Traditional and Herbal Drugs,2014,45(13):1966-1970. |
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| Authors: | NIU Hong-jun LI Bang-dong LI Jun LI Jian-wen and YANG Guan-e |
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| Institution: | Tianjin Modern Vocational Technology College, Tianjin 300350, China;Pharmaceutical Group Bioengineering Co., Ltd., Harbin 150025, China;School of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001, China;School of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001, China;School of Pharmaceutical Science, Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Microbial transformation technology has been applied in the study of Chinese materia medica (CMM) widely. Photosynthetic bacteria biotransformation in the research of Chinese medicine pharmaceutics has become one of the focuses in the field of microbial transformation technology. In this paper, we summarized the pharmacological activity and pharmacodynamic material bases of CMM metabolized by photosynthetic bacteria, in addition, summarized the mechanism of photosynthetic bacteria biotransformation. We also pointed out the problems needed to be studied in the future. |
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| Keywords: | photosynthetic bacteria biotransformation Chinese materia medica material bases of efficacy microbial transformation |
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