妊娠合并甲状腺功能亢进60例临床分析

目的探讨妊娠合并甲亢的诊断、治疗和妊娠结局。方法回顾性分析我院2003年1月～2008年12月收治的妊娠合并甲亢60例患者的资料,按孕期是否正规治疗分为对照组和治疗组,对照组22例,治疗组各38例。结果①甲状腺激素水平:对照组FT3、FT4水平明显高于治疗组,TSH明显降低(P<0.01)。②妊娠结局:对照组引产、早产、流产、小于胎龄儿、死胎发生率高于治疗组(P<0.05)。③妊娠并发症:对照组妊娠糖尿病、妊娠高血压疾病、甲亢性心脏病高于治疗组(P<0.05)。结论妊娠合并甲状腺功能亢进症早期诊断、规范治疗,并定期监测可有效减少母儿并发症的发生,改善妊娠结局。

Clinical Analysis of 60 Pregnant Women with Hyperthyroidism

Objective To study the diagnosis,treatment and pregnant outcome of hyperthyroidism during pregnancy.Methods A retro-spective analysis was conducted for hyperthyroidism during pregnancy admitted to our hospital from January 2003 to December 2008.60 cases were divided two groups,treatment group(n=38) and control group(n=22),according to whether the standardized treatment used or not.Re-sults ①The level of thyroid hormones: The level of FT3,FT4 was great higher in control group than treatment group(P <0.01);The level of TSH was much lower in control group than treatment group(P <0.01).②Pregnant outcome: The incidence of induced labor,premature,abor-tion,small for gestational age infants and fetal death was higher in control group than treatment group(P <0.05);③Pregnant complications: Gestational diabetes,gestational hypertension disease,heart disease from hyperthyroidism were much higher in the control group than those in the treatment group(P <0.05).Conclusion Early diagnosis,treatment and regular monitoring of pregnant women with hyperthyroidism may ef-fectively reduce maternal and fetal complications and improve the pregnant outcome.