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Hypothyroidism induced by anti-epileptic therapy
Authors:S Aanderud  R E Strandjord
Institution:Medical Department B and Department of Neurology, University of Bergen, Haukeland sykehus, Bergen, Norway
Abstract:Two patients on long-term anti-epileptic treatment, one with both phenytoin and carbamazepine, the other with carbamazepine, developed clinical hypothyroidism. Laboratory assays verified the diagnosis. Both patients became euthyroid and the thyroid hormone assays were normal after withdrawal of the drugs.
Keywords:Carbamazepine  hypothyroidism  phenytoin  thyroid funcion  thyrotropin  thyroxine
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