原发性甲状旁腺功能亢进的诊治分析

目的 探讨原发性甲状旁腺功能亢进症（PHPT）的诊断与手术治疗方法.方法 回顾性分析郑州大学第一附属医院甲状腺外科1997年至2009年收治的53例PHPT的临床表现,定性、定位诊断及手术治疗.结果 53例血钙及血清甲状旁腺素均高于正常值.诊断：43例为甲状旁腺腺瘤,6例为甲状旁腺增生,4例为甲状旁腺癌.B超、CT及99mTc-MIBI三项结合可使术前定位准确率达94.3%以上,术后均发生短时的低血钙症.结论 甲状旁腺切除术是治疗PHPT的有效方法,手术成功的关键是术前定位诊断.

Diagnosis and surgical treatment of primary hyperparathyroidism

Objective To evaluate the diagnosis and surgical treatment of primary hyperparathyroidism (PHPT). Methods 53 patients with PHPT who were treated in our hospital from 1997 to 2009 were analyzed retrospectively. Results All patients showed hypercalcemia and elevated parathyroid hormone (PTH). Among them, 43 were diagnosed as parathyroid adenoma, 6 were parathyroid hyperplasia and 4 were parathyroid cancer.The accuracy rate of parathyroid tumor localization was above 94. 3%. All patients presented temporary hypocalcemia after surgery. Conclusions Parathyroidectomy is an effective approach for patients with PHPT. Preoperative localization is essential to the surgery.