远志的化学成分研究(Ⅰ) |
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引用本文: | 姜勇,屠鹏飞.远志的化学成分研究(Ⅰ)[J].中草药,2002,33(10). |
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作者姓名: | 姜勇 屠鹏飞 |
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作者单位: | 北京大学,中医药现代研究中心,北京大学药学院,天然药物学系,北京,100083 |
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摘 要: | 目的研究中药远志Polygalatenuifolia根中的化学成分.方法采用硅胶、Sephadex LH-20及ODS柱层析进行分离纯化,通过理化性质和光谱分析鉴定结构.结果从中分离得到了5个化合物,分别鉴定为tenuifolisideB(Ⅰ),3,4,5-三甲氧基肉桂酸甲酯(Ⅱ),polygalaxanthone Ⅲ(Ⅲ),7-O-methylmangiferin(Ⅳ)和lancerin(Ⅴ).结论化合物Ⅱ和Ⅳ为首次从远志属植物中分离得到,化合物Ⅴ为首次从远志植物中分离得到.
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关 键 词: | 远志 蔗糖酯 酮苷 |
Studies on chemical constituents of root of Polygala tenuifolia (Yuanzhi) Ⅰ |
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Abstract: | Object To study the chemical constituents of the root of traditional Chinese medicine"Yuanzhi" (Polygala tenuifolia Willd. ). Methods Seperation and purification were performed on silicagel, Sephadex LH-20 and ODS CC. Their structures were established on the basis of physicochemical andspectral analysis. Results Five compounds were isolated and identified as tenuifoliside B ( Ⅰ ), methyl 3,4, 5-trimethoxycinnamate ( Ⅱ ), polygalaxanthone Ⅲ (Ⅲ ), 7-O-methylmangiferin ( Ⅳ ) and lancerin( Ⅴ ), respectively. Conclusion Compounds Ⅱ and Ⅳ were isolated from the plant of Polygala L. for thefirst time and compound V was isolated from P. tenuifolia for the first time. |
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Keywords: | Polygala tenuifolia Willd sucrose esters xanthone glycosides |
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