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远志的化学成分研究(Ⅰ)
引用本文:姜勇,屠鹏飞.远志的化学成分研究(Ⅰ)[J].中草药,2002,33(10).
作者姓名:姜勇  屠鹏飞
作者单位:北京大学,中医药现代研究中心,北京大学药学院,天然药物学系,北京,100083
摘    要:目的研究中药远志Polygalatenuifolia根中的化学成分.方法采用硅胶、Sephadex LH-20及ODS柱层析进行分离纯化,通过理化性质和光谱分析鉴定结构.结果从中分离得到了5个化合物,分别鉴定为tenuifolisideB(Ⅰ),3,4,5-三甲氧基肉桂酸甲酯(Ⅱ),polygalaxanthone Ⅲ(Ⅲ),7-O-methylmangiferin(Ⅳ)和lancerin(Ⅴ).结论化合物Ⅱ和Ⅳ为首次从远志属植物中分离得到,化合物Ⅴ为首次从远志植物中分离得到.

关 键 词:远志  蔗糖酯  酮苷

Studies on chemical constituents of root of Polygala tenuifolia (Yuanzhi) Ⅰ
Abstract:Object To study the chemical constituents of the root of traditional Chinese medicine"Yuanzhi" (Polygala tenuifolia Willd. ). Methods Seperation and purification were performed on silicagel, Sephadex LH-20 and ODS CC. Their structures were established on the basis of physicochemical andspectral analysis. Results Five compounds were isolated and identified as tenuifoliside B ( Ⅰ ), methyl 3,4, 5-trimethoxycinnamate ( Ⅱ ), polygalaxanthone Ⅲ (Ⅲ ), 7-O-methylmangiferin ( Ⅳ ) and lancerin( Ⅴ ), respectively. Conclusion Compounds Ⅱ and Ⅳ were isolated from the plant of Polygala L. for thefirst time and compound V was isolated from P. tenuifolia for the first time.
Keywords:Polygala tenuifolia Willd  sucrose esters  xanthone glycosides
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