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环磷酰胺、足叶乙甙加全身照射作急性白血病自体骨髓移植预处理
引用本文:战榕,陈志哲,何桂英,吕联煌,李觉民,林艳娟,许新生.环磷酰胺、足叶乙甙加全身照射作急性白血病自体骨髓移植预处理[J].福建医科大学学报,1993(2).
作者姓名:战榕  陈志哲  何桂英  吕联煌  李觉民  林艳娟  许新生
作者单位:福建省血液病研究所,福建省血液病研究所,福建省血液病研究所,福建省血液病研究所,福建省血液病研究所,福建省血液病研究所,福建省血液病研究所
摘    要:采用环磷酰胺(CTX)50mg/kg、足叶乙甙(VP-16)200mg/m~2(—2,—1天);全身照射(TBI)6.0Gy(0天),为3例急性白血病患者进行不冷冻、不净化自体骨髓移植(ABMT)。移植后患者造血功能重建较顺利,随访病人无病生存期已分别超过27,23,17个月。提示该预处理方案所致的骨髓外毒副作用相对小。

关 键 词:预处理  自体骨髓移植  急性白血病

Cyclophosphamide and Etoposide Plus TBI as Conditioning Regime for Autologoes Bone Marrow Transplantation in Acute Leukemia
Zhan Rong,Chen Zhizhe,He Guiying,et al.Cyclophosphamide and Etoposide Plus TBI as Conditioning Regime for Autologoes Bone Marrow Transplantation in Acute Leukemia[J].Journal of Fujian Medical University,1993(2).
Authors:Zhan Rong  Chen Zhizhe  He Guiying  
Abstract:Unpurged and nocryopreseved ABMTS were carried out in three cases of acute leukemia. The conditioning regimen consisted of cyclophosphamide (50mg/kg/day-2,-1). Etoposide (200mg/m~2/ day-2, -1). TBT (6.0 Gy day 0). No severe complications were observed except for mild nausea vomiting and diarrhea. Swelling parotid glands and stomatitis were noticed, which were disappeared during a short period. The disease-free survivals are more than 27,23 and 17 months since ABMT.
Keywords:Conditioning  auto-bone marrow transplantation  acute leukemia
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