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D-二聚体测定及临床应用研究进展
引用本文:崔树明.D-二聚体测定及临床应用研究进展[J].中国医学检验杂志,2011(1):51-52.
作者姓名:崔树明
作者单位:天津市宝坻区人民医院检验科,天津301800
摘    要:血浆D-二聚体(D—Dimer,D—D)是交联纤维蛋白的特异性降解产物,其水平的升高反映高凝状态和继发纤溶亢进,可作为体内高凝状态和纤溶亢进的分子标志物之一.对高凝状态及纤溶亢进的诊断、疗效观察和预后判断均具有广泛应用价值,近年来,随着方法学的不断进步,D-二聚体检测的临床应用越来越广泛.本文就D-二聚体的检测及临床应用进展综述如下。

关 键 词:D-二聚体  检测  临床应用

ADVANCEMENT IN RESEARCHES OF D -DIMER DETECTION AND ITS CLINICAL APPLICATION
Cui Shuming.ADVANCEMENT IN RESEARCHES OF D -DIMER DETECTION AND ITS CLINICAL APPLICATION[J].Chinese Journal of Medical Laboratory Technology,2011(1):51-52.
Authors:Cui Shuming
Institution:Cui Shuming. (Department of Laboratory Tests, Baodi People's Hospital, Tianjin 301800, China)
Abstract:D - dimer is a specific degradation product of cross linked fibrin in plasma and its increase reflects hypercoagulability and secondary increased fibrinolytic activity. Therefore, it can be used as one of the molecular markers for hypercoagulability and secondary increased fibriolytic activity in body and is of great value for diagnosis, therapeutic efficacy determination and prognosis prediction of the 2 diseases. In recent years, with continuous development in methodology, D - dimer detection has been increasingly used in clinical practice. In this paper, the author reviewed the - D - dimer detection and its clinical application.
Keywords:D - dimer  Detection  Clinical application
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