酚磺乙胺等药物对酶法测定肌酐的干扰及其防治对策探讨 |
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引用本文: | 李家伟,殷昌斌,刘巍,单志娟. 酚磺乙胺等药物对酶法测定肌酐的干扰及其防治对策探讨[J]. 中国医学检验杂志, 2011, 0(2): 60-61 |
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作者姓名: | 李家伟 殷昌斌 刘巍 单志娟 |
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作者单位: | 首都医科大学潞河教学医院检验科,北京101149 |
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摘 要: | [目的]研究酚磺乙胺等药物对酶法测定肌酐的干扰及防治对策。[方法]利用本院临床各科室在一个月中的有关病例的检测材料,用苦味酸法与酶法鉴别干扰的存在,并对材料进行整理分析。[结果]一个月中共检出70例存在负干扰现象。[结论]酚磺乙胺等几种药物对酶法测定肌酐有负干扰,并对其性质、范围、机理及防治对策进行了讨论。
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关 键 词: | 肌酐 酚磺乙胺 酶法 苦味酸法 |
Effects of using etamsylate etc. on determination of creatinine with enzymatic method and measures for its prevention |
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Affiliation: | Li Jiawei, Yin Changbin, Liu Wei, et al. (Clinical Laboratory of Lu He Teaching Hospital, Capital Medical University, Tong zhou 101149, China) |
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Abstract: | [ Objective] TO observe the effects of using etamsylate etc. on creatinine detection with on enzymatic method and explore measures for its prevention. [ Methods ] The medical records of relevant cases in our hospitals in a month were used to determine the inter- ference with picric acid method and enzymatic method, respectively. [Results] In one month, there were 70 cases with negative interfer- ence. [ Conclusion] The ethamsylate etc. has negative interference with detection of creatinine by enzymatic method. Its nature, scope, mechanism and preventive measures are also discussed. |
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Keywords: | Creatinine Ethamsylate Enzymatic method Pieric acid method |
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