探讨磁共振多b值扩散加权成像在前列腺病变中的应用价值

目的探讨MR多b值扩散加权成像(diffusion weighted imaging,DWI)在前列腺病变中的应用价值。材料与方法对病理证实的36例前列腺增生及24例前列腺癌患者进行多b值DWI,b值分别为0、200、400、600、800、1 000 s/mm2,测量病变区的ADC值,并和正常组10名志愿者进行对照。结果 24例前列腺癌患者ADC值随着b值的升高而下降,而36例前列腺增生患者的ADC值随着b值的升高也呈下降趋势,但无统计学差异;对测量结果进行组间单因素方差分析表明,前列腺癌、前列腺增生、正常前列腺外周带及中央腺体区在各组b值之间差异均有统计学意义。结论不同b值的DWI图像所测得ADC值有助于正常组织、前列腺增生和前列腺癌的鉴别诊断。

The diagnostic value of multiple b-value diffusion weighted imaging in prostate disease

Objective: To retrospectively evaluate the diagnostic value of multiple b-value diffusion weighted imaging in prostate disease of MRI. Materials and Methods: Ten healthy volunteers, 36 cases of prostatic hyperplasia (BPH) and 24 cases of prostate cancer (PCa) which pathologically confirmed were included in this study. ADC values were measured at b-value of 200, 400, 600, 800 and 1000 s/mm2 respectively. The quantitative comparison was applied between these groups. Results: With the increase of b value, the ADC value of PCa decreased gradually. However, in BPH patients, the ADC values did not show a significant change. The difference of the b-values of prostate cancer, prostatic hyperplasia and normal prostate tissue had statistical difference between groups. Conclusions: The ADC values of different b-values measured by DWI could help to differentiate between prostatic hyperplasia, prostate cancer and normal prostate.