Immune-inflammatory response in infected arthroplasties |
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| Authors: | S Santavirta Y T Konttinen D Nordstr?m V Bergroth I Antti-Poika A Eskola |
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| Affiliation: | Orthopedic Hospital of the Invalid Foundation, Helsinki, Finland. |
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| Abstract: | We studied the immunocytology of synovial fluid in purulent endoprosthetic infections using cell subtype-specific monoclonal antibodies in avidin-biotin-peroxidase complex staining. Two thirds of the monocytes were CD15-positive, whereas CD2-positive T lymphocytes only formed one third of all the mononuclear cells. The synovial fluid monocyte-activated T-cell ratio differed from findings in sterile inflammatory, reactive and rheumatoid arthritis. |
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