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健康人腮腺α-淀粉酶、溶菌酶的增龄性改变
引用本文:柳晓冰,俞光岩,高岩,庞淑珍.健康人腮腺α-淀粉酶、溶菌酶的增龄性改变[J].中华口腔医学杂志,2001,36(1):37-39.
作者姓名:柳晓冰  俞光岩  高岩  庞淑珍
作者单位:1. 北京大学口腔医学院口腔颌面外科
2. 北京大学口腔医学院病理科
摘    要:目的 观察不同年龄组正常腮腺α-淀粉酶、溶菌酶的分布、含量及增龄性变化的规律。方法 将51例腮腺标本分为4个年龄组,用免疫组化的方法标记α-淀粉酶、溶菌酶,观察记录不同年龄组α-淀粉酶、溶菌酶的染色强度。结果 4个年龄组之间α-淀粉酶、溶菌酶染色阳性率差异有显著性,随着年龄增长,其染色阳性率呈逐渐减低的趋势。结论 HE切片上染色、形态相似的浆液性腺泡之间,实际在功能上存在着很大的不同。α-淀粉酶、溶菌酶增龄性变化的特点与定量组织学研究结果相符合。

关 键 词:α-淀粉酶  溶菌酶  腮腺  增龄性改变  健康人
修稿时间:1999年10月7日

Aging changes of α-amylase and lysozyme in normal parotid gland
LIU Xiaobing ,YU Guangyan,GAO Yan,et al..Aging changes of α-amylase and lysozyme in normal parotid gland[J].Chinese Journal of Stomatology,2001,36(1):37-39.
Authors:LIU Xiaobing  YU Guangyan  GAO Yan  
Institution:Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology, Beijing 100081, China.
Abstract:OBJECTIVE: To investigate the aging changes, the distribution and the content of alpha-amylase, lysozyme in the normal parotid glands. METHODS: Fifty-one specimens of parotid glands with 4 different age groups were studied by immunohistochemical method. The intensity of staining of alpha-amylase, lysozyme was recorded in different age groups. RESULTS: The staining positivity rate of alpha-amylase, lysozyme had striking differences in 4 different age groups and it gradually decreased along with the age increasing. CONCLUSIONS: There are differences among seous acinus which had similar shape and staining in HE slice. The characters of aging changes of alpha-amylase, lysozyme secreted by acinar and intercalated duct cells are conformity with the results of quantitative studies in histology.
Keywords:Alpha  amylase  Muramidase  Parotid gland
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